[Transfusion as passive anti-tetanus prevention in injured patients in shock].
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Biomedical subjects
Publications and source records attributed to L Erdös.
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This is a retrospective analysis out of 49 patients suffering from enterocutaneous fistulae. 25 patients received total parenteral nutrition. The enteral feeding of 17 patients was completed by parenteral nutrition: 7 patients were fed perorally. 13 fistulae (27%) healed up by conservative treatment, 10 underwent surgery and 8 patients had persistent fistulae. The total mortality rate came up to 41%. Total parenteral nutrition can be the only treatment or is an effective adjunct to supplement the surgical management of enterocutaneous fistulae.
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In Hungary the control of immunobiological preparations has been regulated by legal orders since 1938. In the meantime the pertinent rules have been modifed several times, to keep them abreast with current development. The authority of state control has been vested into the Vaccine Control Department of the National Institute of Public Health (OKI), which in this capacity has maintained an intensive collaboration with the producer of immunobiological preparations, the HUMAN Institute of Serobacteriological Production and Research (HUMAN). As a result, several important vaccine preparations (pox, DPT, DT, tetanus, typhoid and BCG vaccines) employed in compulsory immunization programmes have been improved considerably in respect of safety and efficiency, on the basis of laboratory tests, controlled field trials and epidemiological observations, described in detail in this review.
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The influence of the number of insertions of vaccine on smallpox vaccination immunity has been the subject of considerable controversy. In this study the problem was investigated in children of comparable age, sex, and smallpox vaccination history. The incidence of post-vaccinal fever and the antibody response of subjects given single and double insertions were compared. While single insertions caused fewer febrile reactions than double insertions, the difference was not significant. Successful vaccination invariably elicited a marked neutralizing antibody response. However, subjects who received two insertions developed significantly higher antibody titres than subjects with a single insertion. In the revaccinated group the difference in titre was still demonstrable 16 months after vaccination. It is concluded that the number of insertions may play a role in the duration of vaccination immunity.