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Biomedical subjects

L Euller-Ziegler

Publications and source records attributed to L Euller-Ziegler.

At least 55 records · Page 3Linked to original sources

[Systematic study of various tumoral markers in prevalent bone metastasis].

In the presence of prevalent bone metastases, the precise histo-pathological diagnosis of the primary tumor is often difficult. The authors study the diagnostic value of systematic serum assay of a series of tumoral tracers (ACE, AFP, PAP and PSA, SCC, CA 19:9, CA 15:3, CA 125) which until now were used in evolutive and therapeutic monitoring. 34 patients were selected for this preliminary retrospective study (including 20 with a demonstrated histopathological diagnosis). 70 p. cent of prevalent bone metastases express a target tracer corresponding to the initial location. In some cases, an elevated tracer, because of its specificity, may bring about a diagnostic or therapeutic decision (always according to the context). No conclusion may currently be drawn in case of discordance between the anatomo-clinical context and the "profile" of the markers (1 case in our series).

Biomarkers, Tumor↗

Intravertebral vacuum phenomenon in multiple myeloma.

Authors report one case of intravertebral vacuum phenomenon associated with a multiple myeloma. Initially, there occurred a collapse and a lysis of the L4 vertebral body. Two months later, after chemotherapy and cobalt-therapy, X-ray examination showed a vacuum cleft phenomenon within the body of L4 and a backward displacement of the L4 posterior wall. At the same time the patient complained of a cruralgia. Recovery occurred after decompression surgery. Histologic sampling of the L4 vertebral body revealed bone necrosis without any abnormal plasmocytosis. Authors draw attention to the neurological complications occurring in the course of the vertebral necrosis and to the fact that, even in case of multiple myeloma, the occurrence of a transverse vacuum cleft may result from osteonecrosis.

Aged↗

[Treatment of systemic scleroderma with factor XIII in 86 patients, with long-term follow-up].

Eighty-six patients with progressive systemic sclerosis were given coagulation factor XIII intravenously in different dosage regimens. The mean duration of treatment was 19 +/- 18 months and patients were followed up for 22.9 +/- 18.8 months. Improvement or stabilization of the lesions was obtained in 44/86 patients and exclusively concerned skin lesions; there was no improvement in visceral lesions. The drug was well tolerated in short-and long-term treatment. It is concluded that factor XIII demonstrated lasting effectiveness in one-half of the patients treated.

Adult↗

[Rheumatoid polyarthritis and life events].

By applying the systematic and quantitative method of life events to 56 patients with rheumatoid arthritis, the activity of which was assessed both clinically and by means of laboratory tests, the authors demonstrated a significantly higher value for the cumulative life event score over the three years prior to the examination (with or without weighting) in patients in an active phase of the disease compared with patients in remission. These results seem to support the concept that the accumulation of life events may increase the incidence of subsequent episodes of the disease and conversely. The non specific nature of the phenomenon seems to be demonstrated by the study of a control group of subjects hospitalised for disease other than rheumatoid arthritis.

Adult↗

[Finger arthroses].

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Aged↗