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Biomedical subjects

L F Draganich

Publications and source records attributed to L F Draganich.

16 recordsLinked to original sources

Predicting the kinematics and kinetics of gait based on the optimum trajectory of the swing limb.

An algorithm was developed to predict the minimum energy consumption trajectory of the swing limb. The method of dynamic programming, a multistage optimization method, was applied to generate the optimum trajectory of the swing ankle which minimized the mechanical energy required to generate the moments of the joints of the lower extremities during the single support phase of gait. Predictions and measurements of gait were compared for six healthy subjects. The predicted hip and knee flexion angles of the swing limb were not significantly different from those experimentally measured except for hip flexion at times greater than 75% of the swing period. The predicted ground reaction forces were not significantly different from the measured ground reaction forces. Furthermore, the moments about the joints were not significantly different from those computed using the measured ground reaction forces and kinematics of the limbs. The results of this study support the hypothesis that human gait is energy efficient.

Acceleration

Assessment of the posterior malleolus as a restraint to posterior subluxation of the ankle.

We assessed the function of the posterior malleolus, the anterior tibiofibular ligament, and the fibula with regard to posterior stability of the talus in ten ankles of cadavera. Posteriorly directed loads of as much as 200 newtons were applied. Two groups of ankles were tested; in the first group, three ankles in which the ligamentous and osseous structures were intact were tested after transection of the posterior capsule and after removal of 10, 20, 30, and 40 per cent of the articular surface of the distal end of the tibia from the posterolateral corner. In the second group, seven ankles were tested in the same sequence, but the anterior tibiofibular ligament and the fibula were transected before sectioning of the articular surface. Compared with the results for the intact ankle, the experiments on the first group demonstrated less than one millimeter of additional posterior translation of the talus after removal of as much as 40 per cent of the articular surface. In the second group, in which the anterior tibiofibular ligament and the fibula had been transected, significant posterior translation of the talus (more than three millimeters) occurred after removal of 30 per cent of the articular surface (p < 0.01). This represented a 160 per cent increase in translation compared with that in the intact ankle.

Aged

Tensions in the anterior and posterior cruciate ligaments of the knee during passive loading: predicting ligament loads from in situ measurements.

Cruciate ligament tensions were predicted for anteroposterior (AP) tibial translation at 20 degrees, 30 degrees, 80 degrees, and 90 degrees of knee flexion based on in vitro measurements from six cadaver knees. A three-dimensional trigonometric equation was derived to calculate cruciate ligament tension as functions of AP force applied to the tibia and knee flexion angle (KFA). AP forces less than or equal to 150 N were applied. Ligament tension increased with applied AP force. The relationship between ligament tension and applied AP force appeared linear, but a Hotteling's T2 test failed to demonstrate a linear relationship. Tensions in the anterior cruciate ligament (ACL) attained magnitudes of approximately equal to 140 N. Tensions in the posterior cruciate ligament (PCL) attained magnitudes of approximately equal to 220 N. An analysis was performed to determine the sensitivity of ligament tension to hypothetical errors in the experimentally measured parameters used to compute ligament tension. The new method we report can be used to determine tensions in the ligaments of the knee or other joints for various loading conditions.

Adult

The effects of resection of the proximal part of the fibula on stability of the knee and on gait.

We studied six patients to determine the effects of unilateral marginal resection of the proximal part of the fibula on stability of the knee and on gait. At the time of the operation, the fibular collateral ligament and the tendon of the biceps femoris were reattached, but no attempt was made to stabilize the fibula otherwise. The patients were tested an average of sixty-one months after operation. Stability of the knee was measured with an instrumented system. Gait was evaluated with an optical electronic three-dimensional digitizing system and a multicomponent force-platform. The gait of six healthy control subjects of similar age was also studied, and the reproducibility of measurements of stability of the knee was investigated in four healthy adults. There were significant differences between the side on which an operation had been done and the contralateral side with regard to the extent of anterior translation and of total anterior-posterior translation of the tibia at both 20 and 90 degrees of flexion of the knee, and in total varus and valgus rotation of the knee (the number of degrees from a position of maximum varus to one of maximum valgus angulation) at 20 degrees of flexion. The measurements of gait and of motion of the knee were found to be normal when compared with those in the control subjects. In the ground-reaction measurements, there were some significant differences from normal in the medial-lateral plane, but they were clinically unimportant. Resection of the proximal part of the fibula can lead to instability of the knee.

Adult

The effect of marginal osteophytes on reduction of varus-valgus instability in osteoarthritic knees.

The varus-valgus stability of 20 knees with unicompartmental osteoarthritis was studied in vivo at the time of total knee replacement. Intact osteoarthritic knees had an average of 11.0 degrees of varus-valgus motion. Removal of osteophytes from the osteoarthritic compartment significantly increased the motion to 13.1 degrees (P less than 0.05), while subsequent removal of osteophytes from the nonosteoarthritic compartment further increased motion to 14.7 degrees (P less than 0.025). In primarily unicompartmental osteoarthritis, marginal osteophytes appear to stabilize osteoarthritic knees, but can cause fixed deformity.

Aged

An in vitro study of anterior cruciate ligament strain induced by quadriceps and hamstrings forces.

Strain in the anteromedial fibers of the anterior cruciate ligament [ACL(am)] was studied in six cadaver knees. ACL(am) strain was measured in five knees during the application of isometric quadriceps forces alone and simultaneously applied isometric quadriceps and hamstrings forces at 10 degrees increments from 0 degrees to 90 degrees of knee flexion. ACL(am) strain during muscle loading was measured with respect to the ACL(am) strain measured with the knee in its resting position (neutral or near neutral position). A sixth knee was used to investigate the reproducibility of the resting position and quadriceps-induced ACL(am) strains. The strains induced in the ACL(am) by the quadriceps were significantly greater than 0 at knee flexion angles from 0 to 40 degrees and not significantly different from 0 for 50 to 90 degrees. The ACL(am) strains induced by simultaneously applied hamstrings and quadriceps forces were not significantly different from 0 at any of the knee flexion angles tested. Simultaneously applied hamstrings and quadriceps forces significantly reduced ACL(am) strain at 10, 20, and 90 degrees of knee flexion compared to the ACL(am) strain induced by quadriceps forces alone. The hamstrings are potentially capable of both significantly reducing and negating quadriceps-induced ACL(am) strain at 10 and 20 degrees of knee flexion.

Adult

Coactivation of the hamstrings and quadriceps during extension of the knee.

The electromyographic activities of six muscles of the thigh were recorded, using bipolar surface electrodes, during active extension of the knee by six healthy men. The signal amplitudes were normalized to those recorded during isometric maximum voluntary contractions. Extension of the knee from 90 to 0 degrees (full extension) was performed at the rate of 10 degrees per second with the leg unimpeded and with weights of 1.8, 3.6, 5.4, or 7.2 kilograms attached to the ankle. The hamstrings were found to coactivate with the quadriceps during the terminal phase of extension. Coactivation of all three hamstrings was found to occur at joint angles of as much as 9 degrees, with the maximum at full extension of the knee and the strength of the signals ranging to as much as 20 per cent. The signals of all of the flexors and extensors increased with increasing loads on the ankle and, with the exception of the rectus femoris at 9 degrees of flexion, they also increased as the knee extended. The results of this study support the hypothesis that the hamstrings function synergistically with the anterior cruciate ligament to prevent the anterior tibial displacement that is produced by active contraction of the quadriceps in the terminal degrees of extension of the knee. This information is important for the physical conditioning of healthy individuals in preparation for athletic endeavors. Furthermore, if coactivation of the hamstrings with the quadriceps is mediated by sensors other than, or in addition to, those of the anterior cruciate ligament, then strengthening of the hamstrings appears to be an important adjunct to rehabilitation programs after repair or reconstruction of that ligament.

Adult

Interaction between intrinsic knee mechanics and the knee extensor mechanism.

The ability of the quadriceps muscles to extend the knee was studied relative to the intrinsic mechanical features of the knee joint. The quadriceps mechanical efficiency changed by nearly 50% between 0 and 90 degrees of knee flexion. The peak efficiency occurred at approximately 20 degrees of knee flexion. The mechanical efficiency of the quadriceps was dependent on the movement of the net anteroposterior (AP) tibiofemoral contact center of pressure, the change in patellar ligament angle, and the change in the quadriceps-to-ligament force transfer ratio. The average net AP tibiofemoral contact center of pressure moved posteriorly on the tibial plateau as the knee flexed from 0 to 90 degrees. The excision of both cruciate ligaments reversed the posteriorly directed movement of the net AP tibiofemoral contact center of pressure at flexion angles from 60 to 90 degrees, resulting in a reduction in extension moment.

Biomechanical Phenomena

A technique for embedding strain gages within curing bone cement.

A technique has been described to embed strain gages within curing bone cement. Both open faced and encapsulated strain gages were employed. Using a simple cantilever beam in bending test, the experimentally measured strains were linear over the range of bending strains applied and in good agreement with the calculated theoretical values.

Bone Cements

An in vitro study of the Müller anterolateral femorotibial ligament tenodesis in the anterior cruciate ligament deficient knee.

The biomechanical effectiveness of the Müller anterolateral femorotibial ligament (ALFTL) iliotibial band tenodesis on anterior stability and internal rotational stability of the ACL deficient knee was investigated in six cadaver knees. Anterior drawer and internal rotation of the tibia were measured at 15 degrees increments from 0 degrees to 90 degrees in response to 50 N of anteriorly applied tibial force and 3 Nm of internally applied internal torque, respectively, in the intact knee, the ACL excised knee, and following the ALFTL reconstruction. A strain gage was used to measure the resting graft tension and to measure strain in the graft during the load-displacement tests. The Müller ALFTL tenodesis failed to return normal anterior stability to the ACL deficient knee (P less than 0.05). The tenodesis did, however, reduce the anterior laxity of the ACL deficient knee from 30 degrees to 90 degrees of knee flexion (P less than 0.05). The tenodesis overconstrained internal tibial rotation of the ACL excised knee from 30 degrees to 90 degrees (P less than 0.05). Measurements of strain in the tenodesis supported the load-displacement findings that the tenodesis was most effective in constraining anterior drawer and internal tibial rotation from 30 degrees to 90 degrees of knee flexion.

Adult

An in vitro study of an intraarticular and extraarticular reconstruction in the anterior cruciate ligament deficient knee.

The biomechanical effectiveness of an extraarticular ACL reconstruction, an intraarticular ACL reconstruction, and the combination of these on both anterior stability and internal rotational stability of the ACL deficient knee was investigated in six cadaver knees. The extraarticular reconstruction consisted of the Müller anterolateral femorotibial ligament iliotibial band tenodesis, and the intraarticular reconstruction used the middle third of the patellar tendon in the manner of Clancy. The extraarticular reconstruction was found to overconstrain internal tibial rotation of the ACL excised knee between 30 degrees and 90 degrees (P less than 0.05). While the isolated extraarticular reconstruction did not return normal anterior stability to the ACL deficient knee (P less than 0.05), it did significantly reduce the anterior laxity of the ACL deficient knee between 30 degrees and 90 degrees of knee flexion (P less than 0.05). For the combined reconstruction, the intraarticular procedure was performed and then only enough tension was applied to the extraarticular reconstruction to take up slack in the tenodesis without shifting the rotatory position of the tibia from that produced by the intraarticular procedure alone. Neither the intraarticular reconstruction nor the combined procedure resulted in any significant shifts from normal (P less than 0.05) in the rotatory position of the unloaded tibia; during loading neither resulted in rotational displacements significantly different from normal; and both of these procedures reduced the increased anterior laxity of the ACL deficient knee to a level not statistically different from normal. Because the extraarticular reconstruction shared the load when performed with the intraarticular reconstruction as part of a combined procedure, we concluded that it would be useful as an adjunctive procedure in appropriate clinical situations.

Adult

The effect of thigh and goniometer restraints on the reproducibility of the genucom knee analysis system.

We compared the reproducibility of measurements made with the Genucom knee analysis system using two methods of restraint. The first method was that suggested by the manufacturer and consisted of clamping the thigh to the examination chair with 70 N of vertical force and 110 N of mediolateral force and used a single elastic strap to secure the electrogoniometer cuff to the leg. In the second, or enhanced, method, the vertical and mediolateral clamping forces were each increased to 156 N, and an additional strap was used to secure the cuff to the leg. Tests performed were the anteroposterior stress tests at 20 degrees and 90 degrees of knee flexion, and the varus-valgus stress test, the internal-external rotation stress test, and the medial and lateral pivot shift tests at 20 degrees. Five normal subjects were installed and tested on 6 different days with the manufacturer's suggested securing method and on 12 different days with the enhanced securing method. The enhanced method of restraint resulted in significantly reduced day-to-day variance for all tests performed except the varus-valgus stress test.

Adult

Iliotibial band tenodesis: a new strategy for attachment.

We investigated the changes in distance between Gerdy's tubercle on the tibia and points on the posterior two thirds of the lateral surface of the lateral femoral condyle and adjacent lateral femoral shaft in 15 cadaveric knees. A three-dimensional digitizer was used to quantify motion of the knee during flexion ranging from full extension to 120 degrees of flexion. Four load states were applied: internal, external, and neutral rotation, and quadriceps muscles loads based on one third of values in the literature for maximal isometric quadriceps muscles moments. The femoral location most isometric to Gerdy's tubercle was found to be strongly influenced by the load state. A 1.0 cm wide iliotibial band tenodesis was modelled by five straight lines arising from Gerdy's tubercle and attaching to a simulated washer at the junction of the lateral femoral condyle and shaft. Using this model and the motion data obtained from the cadavers, we investigated the effects of quadriceps muscles loading and external rotation of the knee on changes in the distances between these tibial and femoral attachments for each of the five lines. A 180 degrees twist modelled into the tenodesis significantly reduced the range of changes in distance (difference between the largest and smallest changes in distance among the lines for a given angle of flexion) for both of these load states. Therefore, a 180 degrees twist in the tenodesis can enhance isometry among the fibers of the tenodesis. This implies that a 180 degrees twist can enhance load sharing among the fibers of the tenodesis and, therefore, enhance the overall strength of the tenodesis.

Adult

The effect of femoral tunnel position and graft tensioning technique on posterior laxity of the posterior cruciate ligament-reconstructed knee.

We report the effects of femoral tunnel position and graft tensioning technique on posterior laxity of the posterior cruciate ligament-reconstructed knee. An isometric femoral tunnel site was located using a specially designed alignment jig. Additional femoral tunnel positions were located 5 mm proximal and distal to the isometric femoral tunnel. With the graft in the proximal femoral tunnel, graft tension decreased as the knee flexed; with the graft in the distal femoral tunnel, graft tension increased as the knee flexed. When the graft was placed in the isometric femoral tunnel, a nearly isometric graft tension was maintained between 0 degrees and 90 degrees of knee flexion. One technique tested was tensioning the graft at 90 degrees of knee flexion while applying an anterior drawer force of 156 N to the tibia. This technique restored statistically normal posterior stability to the posterior cruciate ligament-deficient knee between 0 degrees and 90 degrees for the distal femoral tunnel position, between 0 degrees and 75 degrees for the isometric tunnel position, and between 0 degrees and 45 degrees for the proximal tunnel position. When the graft was tensioned with the knee in full extension and without the application of an anterior drawer force, posterior translation of the reconstructed knee was significantly different from that of the intact knee between 15 degrees and 90 degrees for all femoral tunnel positions.

Adult