Some aspects of the preclinical study on safety of drugs used in children during experiments on immature animals are presented. Problems of the selection of animal species and the experimental schemes are discussed.

Aging↗

PubMedDate not supplied

[5-hydroxytryptamine and neoplasm growth].

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Adrenal Gland Neoplasms↗

PubMedDate not supplied

[Excretion of 5-hydroxyindoleacetic acid in the urine of sarcoma-45 bearing rats after administration of serotonin, 5-hydroxytryptophan and tryptophan].

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5-Hydroxytryptophan↗

PubMedDate not supplied

[Effect of mexamine on the growth of transplantable tumors].

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Animals↗

PubMedDate not supplied

[Effect of serotonin antagonists and monoamine oxidase inhibitors on the antineoplastic effect of serotonin].

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Animals↗

PubMedDate not supplied

[Effect of serotonin on the antineoplastic activity and toxicity of sarcolysin and dopan].

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Animals↗