PubMed Health⌕ Search

Biomedical subjects

L F Mota

Publications and source records attributed to L F Mota.

5 recordsLinked to original sources
PubMed2001

Computer assisted image analysis methods for evaluation of periodontal wound healing.

The aims of this study were to determine the accuracy of the computer assisted image analysis method and to evaluate its application for the assessment of periodontal wound healing in dogs. Histological material was analyzed with an optic microscope connected to a CCD color camera which transmitted the image to a frame grabber converting the light signals into pixels from which the measurements could be obtained. Twenty sections were read to assess the intra- and inter-examiner reproducibility for the parameters of area filled by new tissue, area of epithelium, area of bone and linear measurements of the cementum. The data were statistically analyzed using the t-test to test the hypothesis that there was no difference between and within examiners. No statistically significant differences were noted (with a confidence interval of 95%) for any parameter when intra-examiner reproducibility was assessed. Similar results were achieved for surface areas when the inter-examiner readings were computed. However, values of linear measurements for cementum showed statistically significant differences between recorders (p < 0.05). Results were consistently uniform and the method demonstrated high accuracy when intra-examiner readings were evaluated.

Alveolar Process↗
PubMed1998

Evaluation of a new bioresorbable barrier to facilitate guided bone regeneration around exposed implant threads. An experimental study in the monkey.

The aim of this study was to evaluate the effectiveness of a new bioresorbable barrier alone or in combination with BioOss for guided bone regeneration around dental implants with exposed implant threads. Five adult Macaca fascicularis monkeys were used in this investigation. After extraction of all premolars and first molars, two endosteal oral implants were installed in each quadrant and the bony defects were randomly treated with either: 1) placement of the new bioresorbable device alone (group 1); 2) placement of the new bioresorbable barrier in combination with BioOss (group 2); 3) placement of an ePTFE barrier in combination with BioOss (group 3); or (4) control (group 4). After a period of six months the animals were killed and the histological processing was performed. There was a significant difference in the amount of new bone regeneration around the implants between the four groups (i.e. groups 1, 2, 3 and 4) (P=0.0122). There was no difference, however, between group 2 and group 3. It can be concluded that the new bioresorbable barrier in combination with BioOss appears to obtain the same results in this type of bony defects as the grafting material in combination with an ePTFE barrier.

Animals↗
PubMed1997

Custom-made root analogue titanium implants placed into extraction sockets. An experimental study in monkeys.

The aim of this investigation was to evaluate clinically and histologically a new custom-made, root analogue titanium implant placed into extraction sockets in monkeys (Macaca fascicularis). Three adult monkeys were used in this investigation. After raising full thickness flaps on the buccal and lingual side, the upper central and lateral incisors were extracted. Each tooth root was machine copied to 1 titanium analogue using a new CAD/CAM-system. The implants were installed in the respective extraction sockets and the flaps sutured back. After 6 months of healing biopsies were taken and processed according to the cutting-grinding technique. The percentage of mineralized bone-to-implant contact was measured as a fraction of the rough implant surface using computer-assisted analysis. The main clinical problem that occurred during implant placement was the fracture of the buccal alveolar wall. The histometric evaluation showed a mean mineralized bone-to-implant contact of 41.2 +/- 20.6%. In this investigation it could be shown that implants fabricated by laser copying will osseointegrate. The presented data encourage the performance of clinical and experimental trials evaluating the new system utilizing improved second generation CAD/CAM equipment. Such studies are currently underway.

Animals↗
PubMed1997

Clinical comparison of resorbable and non-resorbable barriers for guided periodontal tissue regeneration.

The purpose of this study was to compare the clinical results of guided periodontal tissue regeneration (GPTR) using a resorbable barrier manufactured from a copolymer of polylactic and polyglycolic acids (Resolut Regenerative Material) with those of non-resorbable e-PTFE barrier (Gore-Tex Periodontal Material). 12 subjects participated, 6 with similarly paired class II furcations and 6 with 2 similar 2, 3-wall periodontal lesions. The resorbable and non-resorbable barriers were randomly assigned to 1 defect in each subject. Non-resorbable barriers were removed in six weeks. Plaque index (PlI), gingival index (GI), probing depth (PD), clinical attachment level (CAL) and gingival recession (R) were recorded at baseline, (i.e., immediately prior to surgery) and at 12 months postsurgically. The clinical healing was similar and uneventful in both groups. Intrabony pockets depicted significant changes from baseline (p < 0.05) for probing depth reduction and gain in clinical attachment levels. No differences were found between treatments. Class II furcations showed significant improvements from baseline (p < or = 0.05) for probing depth reduction and clinical attachment gain. No differences were detected between treatments. It is concluded that the resorbable barrier tested is as effective as the nonresorbable e-PTFE barrier for the treatment of class II furcations and intrabony defects.

Adult↗