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Biomedical subjects

L F van der Wal

Publications and source records attributed to L F van der Wal.

2 recordsLinked to original sources

Backscatter directivity and integrated backscatter power of arterial tissue.

A 27 MHz transducer, mounted on an ultrasonic microscope, was used to quantify the dependence of backscatter power on the angle of incidence of arterial vessels. Due to variations in the angle of incidence significant variations in backscatter power were found in the intima, the muscular and elastic media, the adventitia and the external elastic lamina. The muscular and the elastic media show anisotropic behaviour in their angle dependence, i.e. the extent of the angle dependence depends on the direction of angle variation. This anisotropic nature is probably caused by the dominant orientation of smooth muscle cells or elastin fibers in these tissue layers. Measurements on 13 specimens of the iliac artery showed that each tissue type of the vessel has its own specific angle dependent behaviour. In the future this property might be used for quantitative tissue characterization.

Humans↗

Angle-dependent backscatter from the arterial wall.

The anisotropic nature of intra-arterial echographic images is reported, and the source of this anisotropy is investigated using postmortem human iliac arteries. A 27 MHz transducer, mounted on an ultrasonic microscope, is used to quantify the angular dependence of the backscatter power versus the angle of incidence, and these results are correlated with histological findings. Besides the observed differences in the acoustic response of morphologically different tissues, significant variations in backscatter power are found in both media and internal elastic lamina due to variations in the angle of incidence. This angle dependence is caused by the dominant orientation of fibers in tissue layers and by the shape and size various scattering particles. The results indicate that long microscopic structures with one main orientation are responsible for the backscattered signal and that the angular-dependent response is related to the histologically determined orientation of these fibers. These results may have an impact on the assessment of intra-arterial echographic images.

Blood Vessels↗