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Biomedical subjects

L Feinkind

Publications and source records attributed to L Feinkind.

8 recordsLinked to original sources

Tubal pregnancy associated with ampullary tubal leiomyoma.

BACKGROUND: Fewer than 100 cases of leiomyoma of the fallopian tube have been described in the literature; most of them are asymptomatic. CASE: A woman presented with a tubal pregnancy which, at laparotomy, proved to be distal to a leiomyoma of the tube. CONCLUSION: Tubal myomas may predispose to tubal implantation of a conceptus. To our knowledge, this is the first time a tubal leiomyoma and a tubal pregnancy have been reported in the English literature.

Adult↗

Umbilical and uterine Doppler velocimetry and prostaglandin levels in preeclampsia.

Eleven preterm patients with severe preeclampsia underwent Doppler velocimetry prior to cesarean section. Maternal venous blood and umbilical arterial and venous samples were collected for prostacyclin and thromboxane determination by radioimmunoassay. Umbilical artery pulsatility index correlated positively with umbilical artery thromboxane B2 levels (r = 0.76; P less than 0.05) and maternal thromboxane levels (r = 0.78; P less than 0.05). We conclude that the vasoactive action of thromboxane A2 may alter placental resistance.

6-Ketoprostaglandin F1 alpha↗

Foot necrosis in a surviving fetus associated with twin-twin transfusion syndrome and monochorionic placenta.

Twin gestations with diamniotic monochorionic placentas have increased perinatal morbidity. We report a case in which, following the death of one member of a set of twins, absent end-diastolic flow was noted. At delivery, we noted thrombosis of placental vessels and vascular connections between the placental vessels of the larger and the smaller twins. The surviving twin was also noted to have necrosis of the right foot, consistent with a thromboembolic phenomenon.

Adult↗

Screening with Doppler velocimetry in labor.

Doppler flow velocimetry was performed on 273 nonselected patients in labor. All patients were at least 2 cm dilated and 80% effaced (58% greater than 4 cm) and were delivered of infants within 24 hours. Fetal heart rate tracing performed at the same time was read by another observer and compared with Doppler flow velocity measurements (systolic/diastolic ratio, pulsatility index). A significant correlation was noted (r = 0.234, p less than 0.001) between the two modalities. Both fetal heart rate tracings and umbilical flow velocity measurements were correlated with fetal outcome. Significant associations were noted between the umbilical systolic/diastolic ratio and fetal distress. 5-minute Apgar scores, the need for intubation independent of gestational age, and umbilical arterial cord pH and base excess. It appears that the information obtained from flow velocimetry had additional benefits compared with that of fetal heart rate tracings alone.

Adult↗

Avoidable causes of perinatal death at or after term pregnancy in an inner-city hospital: medical versus social.

A retrospective analysis of 174 consecutive singleton perinatal deaths at or after term pregnancy in an inner-city hospital was undertaken to determine avoidable causes of death. Adequate material was available in 161 cases. Twenty-eight infants with major malformations were excluded. The remaining 133 infants (95 stillbirths and 38 neonatal deaths) constituted the study population. An avoidable cause was defined as departure from the recognized standards of perinatal care that contributed to the deaths. Avoidable factors were present in 69 of 95 (73%) stillbirths. Contributing maternal/social and obstetric factors were present in 40 of 69 (58%) and 29 of 69 (42%) cases, respectively. Avoidable factors were found in 34 of 38 (89%) neonatal deaths. Contributing obstetric, maternal/social, and pediatric factors were present in 20 of 34 (59%), 12 of 34 (35%), and 2 of 34 (6%) cases, respectively. These results suggest that maternal/social causes were present more often than medical causes as a contributing factor in avoidable perinatal deaths at or after term pregnancy.

Adult↗

HIV in pregnancy.

Human immunodeficiency virus is becoming increasingly common among childbearing women. Through federally recommended testing programs, obstetricians will soon be identifying pregnant women in their practices who are HIV infected. Hence obstetricians must be prepared to face the social, ethical, and medical dilemmas brought on by HIV infection in pregnancy.

Acquired Immunodeficiency Syndrome↗