Biomedical subjects

L Fekete

Publications and source records attributed to L Fekete.

13 recordsLinked to original sources

PubMed2005

Active optical control of the terahertz reflectivity of high-resistivity semiconductors.

We study theoretically and demonstrate experimentally light-controllable terahertz reflectivity of high-resistivity semiconductor wafers. Photocarriers created by interband light absorption form a thin conducting layer at the semiconductor surface, which allows the terahertz reflectivity of the element to be tuned between antireflective (R <3%) and highly reflective (R >85%) limits by means of the intensity and wavelength of the optical illumination.

Journal Article↗

PubMed1999

[Calculated gastric intramucosal pH changes in the early phase of acute pancreatitis].

Based on the literature dysfunction of splanchnic circulation may be assumeol in the development of severe acute pancreatitis. Abnormal gut functions investigated by routinely used clinical examination is not available. Gastric tonometry indirectly gives information about gut function. Authors followed prospectively 12 patients who suffered from acute pancreatitis. Four patients recovered without complications, 4 patients had different complications and 4 patients died. Gastric intramucosal pH (pHi) was measured by TRIP NGS catheter and Tonocap monitor. Measurements were started at the time of hospitalisation and repeated every six hours on the first 3 days. Intramucosal acidosis (pHi < 7.3) could be measured independently from aetiology. Gastric pHi showed strong correlation with Acute Physiology and Chronic Health Evaluation II. (APACHE II) score (p = 0.02). APACHE II scores were significantly higher in-group pHi < 7.2 (13.9 +/- 1.7) compared to group pHi > 7.2 (7.33 +/- 1.06) (p = 0.002). 24-hour changes in APACHE II scores were significantly greater in the cases of pHi < 7.2 (3.3 +/- 1.47) versus pHi > 7.2 (-0.6 +/- 0.97) (p = 0.03). Changes of pHi in the early phase of acute pancreatitis indicate that splanchnic circulation is already involved and the pHi may have a prognostic value.

Acute Disease↗

PubMed1998

Osteochondral resurfacing of the knee joint with allograft. Clinical analysis of 33 cases.

This retrospective clinical study describes three years of experience with cryoprotected-cryopreserved allograft transplantation. During this period 33 knee joints were operated on for different reasons including osteoarthritis, osteochondritis dissecans and post-traumatic surface irregularity. The mean follow-up was nearly two years and the mean age of the patients was 48 years. The grafts were harvested and processed at the West Hungarian Tissue Bank according to the criteria promulgated by the European Association of Tissue Banks. All the operations were performed in the same way. Three types of grafts were used: cylindrical or mushroom-shaped for the femoral condyle and patellar and shell allografts for resurfacing the tibial plateau. Bone matrix gelatine (BMG) and fibrin sealant (Tissucol) were used locally to enhance the revascularisation and to improve the decreased osteoinductivity of the frozen cancellous bone. According to the modified Bentley score, the success rate of the short term follow-up was similar to that of other reported series. An analysis of four biopsies showed that the BMG and fibrin sealant did not appear to affect the viability of the articular cartilage. We conclude that application of these materials is not contra-indicated in allograft surgery.

Adolescent↗

PubMed1997

Effect of endotoxin administration on the severity of acute pancreatitis in two experimental models.

CONCLUSIONS: Endotoxemia can transform acute pancreatitis (AP) into a more severe form of the disease in models of AP provoked by common pancreatico-biliary duct ligation or L-arginine injection. BACKGROUND: It has been shown that systemic endotoxemia is a common feature in severe AP. The effect of endotoxemia on the course of experimental pancreatitis is unknown. METHODS: AP was induced by common pancreatico-biliary duct ligation (experiment 1) and i.p. injection of 250 mg/100 g body wt of L-arginine (experiment 2). Test animals of both experiments received i.p. injections of 0.5 and 1.0 mg/100 g body wt of endotoxin at the induction of AP. Saline-treated and only endotoxin-dosed animals served as controls for both experiments. Mortality rates and pancreatic histology were investigated at 48 h. RESULTS: The mortality rate was significantly elevated (60%, p < 0.05) in experiment 1 when 1.0 mg/100 g of endotoxin was given. In experiment 2, the mortality rate was also increased (30%) at this dose of endotoxin without reaching significance. Histologic changes were more severe in both groups of AP treated by the two doses of endotoxin than without it. Acinar necrosis and hemorrhage were highly elevated (p < 0.01) in both experiments when AP was combined with 1.0 mg/100 g body wt of endotoxin. The animals receiving only endotoxin showed only slight inflammatory and necrotic changes.

Acute Disease↗

PubMed1997

Treatment of ingrowing toenail with segmental chemical ablation.

During a 5 year period (1992-1996) 716 segmental chemical ablations using phenol solution of 80 v/v % were carried out because of ingrowing toenail. As a control, Emmert procedure was done in 200 cases. In the present study we discuss the etiology, the surgical technique of the chemical ablation and the results of the intervention. We have found that phenol treatment results in a larger rate of symptomatic relief, lower recurrence rate and better cosmetic results could be achieved. Taking into account the good results, the low financial requirements of the procedure in the treatment of ingrowing toenail, segmental chemical ablation with phenol may be the therapy of choice of the disease.

Combined Modality Therapy↗

PubMed1996

A mushroom-shaped osteochondral patella allograft.

Replacement of the damaged chondral surface of the patella is often difficult because of the high mechanical stresses and the relatively thin cancellous surfaces. A new method has been developed to resurface the whole gliding surface with a mushroom-shaped allograft which provides firm fixation and an excellent base for rapid revascularisation. Fibrin gives additional stability and bonematrix gelatin (BMG) is used to enhance creeping substitution. Immediate motion and weightbearing promote rapid rehabilitation.

Cryopreservation↗

PubMed1981

Blood coagulation in healthy and severely ill newborn infants.

Normal values of blood coagulation factors were investigated in 30 healthy newborn infants. On the basis of these normal standards 8 infants with DIC were evaluated. All of them had serious underlying diseases. By appropriate treatment of the primary disorder and replacement of depleted procoagulants, the bleeding disorder disappeared in six of eight patients without heparinization. Diagnostic criteria and management of neonatal disseminated intravascular coagulation are discussed.

Blood Coagulation↗

PubMed1976