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Biomedical subjects

L Flores de Jacoby

Publications and source records attributed to L Flores de Jacoby.

At least 19 recordsLinked to original sources
PubMed1990

Periodontal alterations in patients with pemphigus vulgaris taking steroids. A biannual assessment.

Periodontal health parameters and salivary cortisol were studied in 19 adult pemphigus vulgaris patients on chronic steroid therapy. The patient population was divided into non-medicated and medicated subjects at intake into the study. A significant difference between the 2 examinations, performed at an interval of 8.73 months +/- 4.35, was found in bleeding index (p less than 0.000 and p less than 0.04, respectively) and gingival recession (p less than 0.000 and p less than 0.009) in both groups. No changes occurred in alveolar bone height. Steroid therapy altered the bleeding index (R = 0.60 and R = 0.80) and gingival recession (R = 0.87 and 0.91) in a dose-related manner, and induced low salivary cortisol. The findings of this study would suggest suppression of the host inflammatory reaction, resulting in an alleged healthy clinical appearance of the periodontium.

Adolescent↗
PubMed1987

Distribution of morphologically different micro-organisms associated with active periodontal lesions.

The morphological composition of the subgingival plaque associated with active periodontitis lesions and comparable inactive control lesions were determined in a 36-year-old patient with advanced periodontal disease. Monthly measurements of the clinical attachment level were subjected to linear regression analysis as a function of time. Attachment loss was recorded during the monitoring period at 10 sites, with loss of 2 mm or more at 6 sites. Plaque samples taken from these 6 sites and from 6 control sites with similar clinical conditions were not of uniform composition. Active lesions harboured on average 46% more cocci and twice as many large spirochetes as inactive control lesions. A linear regression analysis of the proportions of different morphotypes in the subgingival plaque versus the calculated monthly attachment loss rate at the time of sampling provided only very weak correlations, if at all. The observations made in the patient under investigation suggest that there is no great probability of suspected differences in the floras of active and inactive lesions being detected by dark-field analysis alone. The role of motile rods and spirochetes may have been over-rated hitherto.

Adult↗
PubMed1979

[Comparative clinical and histological studies on keratinized and non-keratinized tissues transplanted onto the periosteum and the denuded alveolar bone].

Our clinical and histological investigations in humans and beagle dogs in a unilateral trial with free and pedicled grafts applied to the periosteum and to exposed alveolar bone established that from the clinical aspect it is better to place the graft on the exposed bone to obtain a firmly fixed base instead of a movable periosteal one.

Alveolar Process↗
PubMed1979

[The presentation of the periodontal blood vessels. Histological studies in perfused rats].

Unbroken series of sections taken from various areas of the periodontium of vitally fixed rats were prepared as the basis for constructing a model for the morphology of the vessels and for planimetric evaluation. Using this material, we were successfully able to validate a technique for localization, course, and distribution of vessels and of capillary anastomoses.

Animals↗
PubMed1979

[Modern aspects of dental photography].

Potential areas of application for dental photography were described. The choice of the camera body depends on the intended use. The Medical Nikkor 5.6/200 and the Yashica Medical 100 lenses as well as an extension tube with approximately 100 mm focal distance may be used; the latter is best combined with a circular flash unit or one to two standard flash units. A cheek-holder and mirror are necessary. A few practical tips were presented.

Diagnosis, Oral↗
PubMed1979

[The use of organic bone matrix as material for direct pulp capping].

The effect of bone matrix soaked in thyrocalcitonin on vitally amputated pulp was studied in beagle dogs with light and electron microscopy. All treated teeth were vital after eight weeks; the area of implantation was densely populated with cells. Formation of hard tissue differing from normal dentinogenesis had begun.

Animals↗
PubMed1978

[Electron microscopic studies on pedicled grafts of alveolar mucosa and on newly formed periosteal epithelium].

20 patients who had undergone a vestibuloplasty using the technique of Edlan and Mejchar were examined by histo-morphological studies of the transplanted alveolar mucosa and the epithelialised periosteal zone up to one year post-operatively. The following conclusions were reached: --the original characteristics of the transplanted tissue remain unaltered. --numerous abnormalities in the epithelium and connective tissue are explained by insufficient oxygen diffusion and marked inflammatory reaction in the connective tissue. --there is no keratin formation although the number of layers of the stratum superficiale increases after the 16th post-operative week. On the basis of these results the question of whether there is a possible change-over from uncornified to a cornified epithelium is answered in the negative.

Adolescent↗