Idiopathic retroperitoneal fibrosis simulating renal malignancy.
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Biomedical subjects
Publications and source records attributed to L Forzini.
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Computed Tomography (CT) was employed to evaluate the incidence of brain and adrenal gland metastases in 74 patients (not-small cell lung cancer) staged for surgery. Nine patients presented one or more asymptomatic brain metastases, 4 adenocarcinomas, 3 epidermoid, 2 adenosquamous. In 6 cases adrenal gland masses were found, only one of which was confirmed as a secondary lesion at biopsy. The authors conclude that brain CT is useful in the preoperative staging of lung cancers, independent of the histology of the primary lesion. An accurate assessment of the utility of CT of the adrenal glands requires a larger sample of patients due to the high incidence of benign adrenal gland masses.
The value of CT and lymphography of the retroperitoneum was compared in 31 patients with testicular tumors. In no patient with normal or equivocal lymphography was more information gained by CT. In abnormal cases, the presence of metastatic deposits was well detected at both examinations, but CT proved more useful in defining the exact extent of the tumor and facilitated the proper arrangement of the irradiation fields. A strategy in the sequence of investigation in testicular tumors is suggested, aiming to save CT time when CT information is not likely to be of significance for treatment planning.
A critical and comparative analysis between chest radiograms and CT pictures in pulmonary fibrosis of various degree, occurring in farmer's lung, reveal that the latter are apt to give a somewhat more diversified informations about pulmonary changes as simple radiography. This would prove useful in evaluating the extension and distribution of anatomical changes due to fibrotic process, although as far not able to allow an earlier diagnosis.
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Two groups of subjects, ranging from 20 to 40 years of age the first and from 65 to 85 years the second, have been submitted to bone density measurements by EMI CT 5005 All-Purpose Scanner (140 kV; 28 mAs) and the average values compared. The difference between the average values of the two groups has been taken as a scale of points to evaluate the mineral contents of bone. By the group of older subjects the loss in trabecular bone (lumbar spine L2/L3) proved to be 59.51 EMI units, corresponding to the 47.6% of the mineral contents (p = < 0.01); the loss in compact bone (femur) was 6.6 EMI units corresponding to 5.28% of the mineral contents (p = < 5). The trabecular bone and compact bone average values added together give a whole-skeleton mineral contents index. This index applied to the group of older subjects showed a diminution of 65.81 EMI units indicating a 52.6% loss of mineral contents. Repeated measurements taken at a distance of time proved the method to be fairly reliable with acceptable degree of accuracy (+/- 5%). A tentative approach to clinical use of the skeletal index gave satisfying results.
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