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Biomedical subjects

L Friesen

Publications and source records attributed to L Friesen.

6 recordsLinked to original sources

Developing collaborative research between clinical agencies: a consortium approach.

Collaborative research is receiving increased attention because it maximizes scarce resources and can increase research productivity. One form of collaboration, the consortium approach, was used by six hospitals in northern California and Nevada to increase research activity among the agencies. Our experience with this consortium approach is described. Advantages and disadvantages of this approach to facilitate collaborative research are presented. This approach is recommended for clinical agencies in geographic proximity with similar clinical concerns and administrators supportive of research activity.

Humans

Retention of Basic Cardiac Life Support content: the effect of two teaching methods.

Does the method of instruction affect retention of Basic Cardiac Life Support (BCLS) knowledge and skill? This was the primary question addressed in a study conducted in a university school of nursing. The teaching methods studied were a lecture-demonstration-return demonstration method and a self-paced method. The sample consisted of 63 baccalaureate nursing students who were assigned to one of the two teaching methods. American Heart Association instructional materials and cognitive and performance tests were used with both treatment groups. Initial mastery and retention were tested during week two and eight respectively. Cognitive knowledge was retained at a mastery level by both groups at eight weeks. In addition, there was no difference in retention of performance skills based on teaching methods. However, neither group was able to demonstrate retention of performance skills at a mastery level. Additional data indicate the self-paced subjects spent less time in BCLS learning activities. While the self-paced instructional package was more costly on a one-time basis, repeated applications would decrease the cost/student.

Adult

An anticoagulant for transport of bovine blood.

Various anticoagulant were assessed in order to develop a transport media for bovine blood which would improve leukocyte stability. The effects of time, disease in the donor and different personnel and laboratory equipment were also tested. The transport media most effective for leukocyte stability was found to be Titriplex IV. This is a modification of Titriplex I by the inclusion of acetylsalicyclic acid to prevent cellular clumping and by the removal of methylene blue. Anticoagulant citrate dextroseformalin-ASA performed equally well for transport but cellular morphology was impaired. Febrile or neoplastic disease in the donor animal did not alter the efficiency of the formalin containing anticoagulants.

Animals

A clinical preceptor program: strategy for new graduate orientation.

The nurse internship program offers a practical approach to the orientation of new graduates to hospital routine. Staff nurses, as clinical preceptors, provide peer role models and clinical support for new graduates during their transition from student to staff nurse. From their experience in developing the program, the authors discuss the theoretical basis, the pragmatics, and the benefits of this approach and suggest its applicability to other situations.

Clinical Competence

Cytologic evaluation of breast fluid in the detection of breast disease.

The availability and cell content of aspirated breast fluid from 1,706 women were evaluated to determine the usefulness of breast fluid cytology as an indicator of breast disease. A newly developed aspirator was used to obtain cells adequate for diagnosis from approximately 50% of the women tested. Fluids were most readily available from women between the ages of 30 and 50 years. Although abnormal cytologies were observed in all age groups, the relative proportion of abnormal specimens as well as the degree of abnormality increased as a function of age. More women over 40 years of age with a high risk of breast cancer had cells classified in the more abnormal categories than did women in the normal risk group. To localize otherwise occult lesions, contrast ductography was performed on all women with very abnormal ductal cells. Women with atypical hyperplastic cytologies most commonly had benign and premalignant breast disease at subsequent biopsy. Of 27 women with fluids classified as suspected carcinomas 18 (66%) had small carcinomas. These observations strongly suggested that the presence of atypical cells in aspirated breast fluids has important clinical application for early detection of breast cancer. One limitation of cytology was that the technique rarely detected carcinomas greater than 1 cm.

Adult