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Biomedical subjects

L Fung

Publications and source records attributed to L Fung.

22 records · Page 2Linked to original sources

Life event stress and chronic difficulties in duodenal ulcer: a case control study.

In a sample of consecutive ulcer (DU) patients and age, sex and social class matched normal controls, the prevalence of antecedent stressful life events in the two samples was similar. Antecedent chronic difficulties often lasting years were however significantly more common in the ulcer patients. Duodenal ulcer was more common in divorced, separated or widowed subjects; this finding was explained by the fact that these subjects had more chronic difficulties which predisposed to ulcer disease.

Adult↗

A systematic review of the effectiveness of environmental awareness interventions.

PURPOSE: To evaluate and summarize evidence on the effectiveness of interventions available to public health staff regarding the protection of the public from environmental risks. METHOD: This systematic review involved a comprehensive literature search, screening for relevance, quality assessment of relevant studies, data extraction and synthesis. RESULTS: Fourteen of 65 relevant studies were of 'moderate' or 'strong' quality. Intervention types in these 14 studies included: mass campaign, counselling, school curriculum, educational sessions, and distribution of printed materials. Short-term improvements in awareness or knowledge were observed in 13 of the 14 studies. Eight of 13 studies that examined behavioural outcomes observed short-term improvements in self-reported behavioural outcomes. CONCLUSIONS: Positive short-term changes in health-protective awareness, knowledge and self-reported behaviour appear to be associated with relatively intensive interventions that use multiple methods and settings, and/or are delivered over multiple sessions.

Awareness↗

Effect of T-lymphocyte depletion on the pathogenesis of marble spleen disease virus infection in ring-necked pheasants.

The purpose of this study was to determine the effect of cyclosporine (CSP)-mediated T-lymphocyte depletion on the pathogenesis of marble spleen disease virus (MSDV) infection in ring-necked pheasants. Seventy-two 6-week-old pheasants were divided into three groups; one group of 18 birds was inoculated with MSDV, a second group of 18 birds was treated with CSP, and a third group of 36 birds was both treated with CSP and inoculated with MSDV. Two birds each from both of the smaller groups and four birds from the largest study group were necropsied periodically over a 14-day period. T-lymphoblastogenesis assays documented significant T-cell depression in the CSP-treated groups. Routine histology and immunohistochemical staining for MSDV antigen demonstrated that the CSP-treated MSDV-inoculated birds had higher lesion incidence, had wider tissue distribution of virus, and retained virus in tissues longer than did the MSDV-inoculated-only birds. These results indicate that T-lymphocytes play a role in the host response to infection with MSDV.

Adenoviridae Infections↗