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Biomedical subjects

L G Erokhina

Publications and source records attributed to L G Erokhina.

At least 19 recordsLinked to original sources
PubMed1999

[Myasthenia onset in elderly patients].

Possibility of myasthenia debut at old age is shown. 5 cases of 73-87 year-olds with the diagnosis-generalized form of myasthenia are reported. Peculiarities of clinical manifestations in this age group are described. Polymorbidity in the individuals of old age is noted. It is recommended to include vasoactive preparations in the scheme of therapy.

Age Factors↗
PubMed1994

[The computer diagnosis and prognosis of emergency states in neurology].

The authors provide the analysis of long-term experience gained in the field of devising and introduction of diagnostic algorithms adjusted for various mathematical approaches and aimed for resolving of clinical tasks in vascular and somatogenic impairments of the nervous system. Basic requirements have been formulated for effective use of the diagnostic tables. The authors suggest to compare on the training sample diverse mathematical methods in order to define most effective of them in each case. The application of artificial file of observations is important to determine maximum accuracy of the diagnostic system. An advantage of multivariate statistical methods is demonstrated in clinical decisions on the treatment of somatogenic nervous diseases.

Algorithms↗
PubMed1992

Long-term preservation of microbial ecosystems in permafrost.

It has been established that significant numbers (up to 10 million cells per gram of sample) of living microorganisms of various ecological and morphological groups have been preserved under permafrost conditions, at temperatures ranging from -9 to -13 degrees C and depths of up to 100 m, for thousands and sometimes millions of years. Preserved since the formation of permafrost in sand-clay sediments of the Pliocene-Quaternary period and in paleosols and peats buried among them, these cells art the only living organisms that have survived for a geologically significant period of time. The complexity of the microbial community preserved varies with the age of the permafrost. Eukaryotes are found only in Holocene sediments; while prokaryotes are found to greater ages, i.e., Pliocene and Pleistocene. The diversity of microorganisms decreases with increasing age of sediments, and as a result cocci and corynebacteria are predominant. Enzyme activity (catalase and hydrolytic enzymes) and photosynthetic pigments (chlorophyll and pheophytin have also been detected in permafrost sediments. These results permit us to outline some approaches to the search for traces of life in the permafrost of Martian sediments by borehole core sampling. It is in the deep horizons (and not on the planet surface), isolated by permafrost from the external conditions, that results similar to those obtained on Earth can be expected.

Bacteria↗
PubMed1990

[Elaboration and use of the methods of computer-assisted diagnosis of cerebrovascular pathology].

The purpose of the work was to analyze the experience with the trial of diagnostic algorithms to specify possibilities of differential diagnosis and forecasting the course or outcome of cerebrovascular diseases. Detailed study of 922 clinico-anatomic cases (547 with hemorrhagic brain stroke, 157 with ischemic, 218 with pseudostroke) enabled revealing differential-diagnostic criteria for the pathological patterns under study bearing in mind disease pathomorphism. Analysis was made of the tabular diagnosis of cerebrovascular pathology and of the experience gained with the trail of diverse diagnostic algorithms for staged diagnosis of brain stroke and pseudostroke, different varieties of cerebral hemorrhages (10 varieties). The results of the use of four algorithms for forecasting hemorrhagic brain stroke were studied and compared. The accuracy of the diagnosis and forecasting amounts from 55 to 82.3% depending on the problem to be solved and the algorithm used. The data show the necessity of the careful providing of the algorithm choice as dependent on the problem raised.

Adult↗
PubMed1990

[Global amnesia syndrome among the initial clinical manifestations of brain tumors].

Global amnesia is observable in different lesions of the nervous system, including glial tumors of the brain. It is emphasized that global amnesia may turn out to be the first clinical manifestation of brain tumors. In such a case severe mnemonic disorders are likely to regress under the influence of vasoactive and dehydration therapy, which does not exclude, however, their tumorous genesis. These data should be taken into consideration during analysis of mnemonic disorders in neurological patients. All the patients with the above syndrome should be subjected to a long follow-up even in cases where the syndrome completely regresses under the therapeutic influence.

Amnesia↗
PubMed1987

[Transient global amnesia syndrome].

Nine patients with the syndrome of transitory global amnesia (TGA) have been examined. The authors present the clinical characteristics of the syndrome, describe the differential diagnosis, forms and course of the syndrome, as well as methods of its treatment and prognosis. It has been demonstrated that the syndrome of TGA may develop in the presence of both primary cerebral pathology (insufficient circulation in the vertebrobasilar system) and general pathogenic impacts leading to impairment of the systemic and cerebral hemodynamics. It has been established that transient recurrent mnemonic disturbances during the follow-up are associated with the formation of a stable Korsakoff's syndrome. Methods of therapy of these disorders have been developed and the diagnostic and prognostic significance of neuropsychological examination has been demonstrated.

Adult↗