[Dispensary follow-up of children affected with diseases of the blood].
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Ambulatory Care↗
Biomedical subjects
L G Kuz'menko
Publications and source records attributed to L G Kuz'menko.
[Use of lactusan for the correction of microecological intestinal disturbances in children].
The study demonstrated that lactusan (lactulose) could be used as an effective remedy in dysbacteriosis. Twenty four sick children aged 1 month to 15 years were examined. Administration of lactusan to 21 patients resulted in perceptible improvement of clinical symptoms, mainly to the cessation of diarrhea. In 14 children an increase in the population level of bifidobacteria and lactic acid bacteria and a decrease in the number of opportunistic microorganisms were observed. Lactulose should be referred to prebiotics.
Adolescent↗
[Detection of mycoplasma antigens and immune complexes in sera of the children with bronchial asthma].
The study was targeted at revealing Mycoplasma pneumoniae (M.p.) and Mycoplasma hominis (M.h.) antigens in blood samples of children with bronchial asthma (BA),both in a free state and those included in circulating immune complexes (CIC). The mycoplasma antigens of one or both species have been detected in one third out of 62 patients with BA. In this group of patients the frequency of detection of specific antibodies twice exceeded that of mycoplasma antigens. Testing paired blood samples of children with BA (n=26) showed, that at receipt in a hospital and a month after primary examination the mycoplasma antigens were detected in 16 and 12 patients, respectively, the association of M.p. and M.h. antigens being more frequent. Data on distribution of antibodies according to immunoglobulin classes testify that basically two (M, G), or four (M, G, A, E) classes were registered in children, the M class antibodies in high percentage of cases (from 36.6 up to 50.0%)being detected in every term of examination. These data indirectly testify that the antigens can be partly included in the CIC structure. The level of the total CIC content in BA children's blood sera one month after hospitalization twice exceeded the value detected at primary examination. Three months later later this parameter decreased not reaching the control value. The differential analysis of the precipitated CIC within the whole period of examination showed that mycoplasma antigens were present in the CIC structure in 87.4 - 65.0% of cases. The data obtained precondition future studies on the role of mycoplasma and M.p. and M.h. antigens included in the CIC in the pathogenesis of BA.
Adolescent↗
[Leukemia, lymphogranulomatosis and histiocytosis of Langerhans in children with a history of enlarged thymus gland].
The group consisted of 1056 children with enlarged thymus and a monitored catamnesis in 317 of 0.5-23 years. In 5 examinations in different periods after the diagnosis of enlarged thymus, haematological malignancies were diagnosed: acute lymphoblastic leukaemia (2 children), lymphogranulomatosis (1 child), chronic myeloid leukaemia (monocytic variant) and histiocytosis of Langerhans (1 child). The comparison of these data with other publications on the prevalence of these diseases in the population and the rate of mortality in Moscow place the children with enlarged thymus to high-risk group for haematological malignancies.
Female↗