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Biomedical subjects

L G Marchenko

Publications and source records attributed to L G Marchenko.

17 recordsLinked to original sources

[On clinical manifestations of rotavirus-related gastroenteritis and possible links with its viral phoretype].

The results are presented of the study of rotavirus gastroenteritis course in 45 patients (23 children and 22 adults) with different phoretypes. Phoretypical heterogeneity of rotavirus population was discovered among which the "long" phoretype prevailed. Rotavirus infection ran with diverse clinical symptoms: mild, moderate and severe. A lethal outcome occurred in an old male patient. No correlation was found between the phoretype and severity of the disease.

Adolescent↗

[Surgical treatment of bilateral pulmonary tuberculosis].

Two hundred and eighty two patients with different types of bilateral tuberculous lesion of the lung were operated on. Most (n = 124) patients underwent consecutive operations, 106 one-stage resections of the lung through transsternal access on the one side and video thoracoscopic resections on the other. One-stage bilateral video thoracoscopic operations were made in 52 cases. The greatest number of postoperative complications was noted with multistage operations, which is accounted for a critically ill patient group, advanced processes, concurrent pyoseptic infection. The patients undergone-transsternal resections showed minimum mortality rates with a rather low incidence of postoperative complications.

Adolescent↗

[Clinical and laboratory characteristics of rotavirus infection in adults].

The paper provides clinical and laboratory characteristics of 21 patients aged 20-80 years who had rotavirus infection, including 52% of 51-80-year-old inpatients. Recovery was observed in 15 cases, 6 patients died. The paper also characterizes the clinical course of rotavirus infection in the hospital setting and presents autopsy findings of the 6 decreased patients. The manifestations specific for rotavirus infection were identified to be involvement of serous and mucosal membranes predominantly of the small intestine, frequent development of serous peritonitis, as well as generalization of an infectious process afflicting the gallbladder, liver, heart, lung, and kidney.

Adult↗

[Molecular epidemiology of rotaviruses circulating among residents of St. Petersburg from 1986 through 1991].

The results of screening of 510 patients with acute gastrointestinal diseases over the period of 1986 to 1991 are presented. Rotaviruses were shown to be the infection agents in 112 (60%) children and 76 (40%) adults. The phoretyping of the isolated strains revealed cocirculation of 17 different phoretypes of rotaviruses: 8 "long" and 9 "short" ones. At the same time, two predominant phoretypes were found to alternately circulate in various epidemic seasons. The "long" phoretypes were found to be equally prevalent among adults and children, whereas the "short" phoretype rotaviruses were isolated mainly from children. The cyclic pattern of circulation of rotavirus phoretypes and genetic changeability of these viruses as a factor determining the prevalence of rotaviral infection are discussed.

Adult↗

[Virus carriers in rotavirus infection].

Discusses the effects of various factors on the expression of asymptomatic virus carriership and validates the need in laboratory screening of risk groups including children aged under 5 years and elderly subjects aged over 60. During outbreaks of rotaviral infection virus carriership among healthy subjects may be as high as 34.6%.

Carrier State↗