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Biomedical subjects

L G Ost

Publications and source records attributed to L G Ost.

At least 73 records · Page 4Linked to original sources
PubMed1984

Electrodermal non-responding in schizophrenia: relationships to attentional, clinical, biochemical, computed tomographical and genetic factors.

The purpose of the present study was to examine whether a psychophysiologically delineated subgroup of electrodermally non-responding subjects show deviations in other data domains. Specifically, we examined clinical ratings of psychopathology, cognitive measures of distractibility in short-term memory, family history of schizophrenia, as well as biochemical indices of monoamine and endorphin activity, and measures derived from computed tomography. The non-responders had significantly lower skin conductance level, less spontaneous fluctuations, and a smaller ratio of elicited to spontaneous responses. The non-responders had a significantly higher incidence of schizophrenic relatives than the responders, and tended to show more psychotic symptoms. The two groups did not differ in cognitive distractibility, or in biochemical and computed tomographical measures.

Adolescent↗
PubMed1982

Self-control procedures in biofeedback: a review of temperature biofeedback in the treatment of migraine.

It is argued that in order to optimize the achievement of self-control and to evaluate the clinical effects of biofeedback three skills should be included in training and assessment, namely: (1) the ability of voluntary control with external feedback, (2) the ability of voluntary control without external feedback, and (3) the ability to apply the self-control skill in critical situations in everyday life. A review of the literature concerning temperature-biofeedback in the treatment of migraine headaches shows that the research from this point of view is in a rather poor state of affairs and that no definite conclusion can in fact be drawn about the degree of self-control which has been achieved and hence of the ultimate clinical value of biofeedback.

Biofeedback, Psychology↗
PubMed1977

Thyrotropin-releasing hormone (TRH) inchronic schizophrenia. A controlled study.

A controlled study on the effect of synthetic Thyrotropin-Releasing Hormone (TRH) versus placebo in 10 drug-free chronic schizophrenics is presented. TRH 600 mug or placebo was administered intravenously on 4 consecutive days in a double-blind cross-over design and the schizophrenic symptoms were scored daily by use of two rating scales (CPRS and NOSIE). Blood samples were taken before and 30 and 45 minutes after the first and the fourth injection and analyzed for TSH. No changes in symptom intensity were found during the TRH or placebo treatment period and no difference was obtained between the two treatments. The dose of TRH used caused a significant increase in the plasma level of TSH which indicated a normal pituitary responsiveness to TRH. The data do not support the notion that TRH has a beneficial effect in chronic schizophrenic patients.

Adult↗