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Biomedical subjects

L G Selbovitz

Publications and source records attributed to L G Selbovitz.

5 recordsLinked to original sources

A method to track surgical site infections.

We present an approach to assessing the impact of surveillance for surgical site infections and providing feedback to surgeons on their progress, as part of continuous quality improvement. Adjusting for patient risk factors using the Standardized Mortality Ratio, there was a marked decrease over time in both SMR (1.3 to 0.27) and crude infection rates (32 to 10 per thousand operations per year). These declines cannot be explained by decreased length of hospital stay.

Benchmarking↗

Continuous quality improvement and physician training.

Continuous quality improvement (CQI) is a system of management that permits individuals to develop an organized approach to improvement. The fundamental tenets of CQI are applicable at the bedside and in the training of residents because they permit the development of a consistent approach to clinical variability and uncertainty. When the principles of CQI are applied to the daily practice of medicine, they not only enhance the educational process but also provide a framework for the continuing quest for knowledge. In that context, these principles can provide a continuing stimulus and challenge to physicians and can enhance the patient-physician relationship that lies at the core of any effort to integrate CQI into patient care.

Hospitals, Teaching↗

Erythrocyte sensitization with monomeric IgM in a patient with hemolytic anemia.

An automated antiglobulin test showed that erythrocytes of a patient with an acute episode of Coombs-negative hemolytic anemia were strongly sensitized with nonagglutinating IgM molecules. The bound antibodies, after elution from red blood cell stroma, were found to be monomeric IgM, since they migrated with IgG molecules on an agarose column, although they were proved to be immunoglobulin M, not G, by a sensitive hemagglutination inhibition assay. The hemolysis subsided with steroid therapy, but ANA increased to a titer greater than 1,024 (with peripheral pattern) without other laboratory evidence of systemic lupus erythematosus. In addition, the patient demonstrated photosensitivity and nonscarring alopecia. We consider that this appearance of erythrocyte autoantibodies consisting of monomeric IgM was a symptom of atypical SLE.

Aged↗