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Biomedical subjects

L G Wohl

Publications and source records attributed to L G Wohl.

3 recordsLinked to original sources

Pseudophakic phacoanaphylactic endophthalmitis.

Two cases of pseudophakic phacoanaphylactic endophthalmitis are reported. Both responded favorably to a total posterior capsulectomy performed in addition to removal of the intraocular lens and remaining cortical material. Current theories on phacoanaphylactic endophthalmitis are discussed. Excision of the entire posterior capsule with anterior capsular flaps and entrapped cortex is emphasized as an integral part of the treatment of this condition.

Aged↗

Effectivity of laser ridge intraocular lenses.

Two hundred fifty intraocular lenses with varying sizes of laser ridges were implanted following extracapsular cataract surgery to determine the effectivity of the laser ridge in creating a space between the intraocular lens and the posterior capsule. Six weeks post-operatively, the distance between the intraocular lens and the posterior capsule was judged as adequate in 92% of cases with a .35 mm ridge, 88% cases with a .25 mm ridge, and 80% of those with a .15 mm ridge. A group of non-angulated, non-ridged lenses placed out of the capsular bag had an adequate space in 82% of cases, and a group of non-angulated, non-ridged lenses placed in the capsular bag had only 44% adequate spaces. Intraocular lenses with laser ridges should be used to enhance the space between the intraocular lens and the posterior capsule, thus increasing the safety of postoperative Nd:YAG laser posterior capsulotomy.

Evaluation Studies as Topic↗

Metastatic bacterial endophthalmitis: a contemporary reappraisal.

Metastatic bacterial endophthalmitis remains a challenge to the clinician despite the success of antibiotics in reducing its frequency and severity. Controversy currently surrounds the management of this condition because of uncertainty about the value of and indications for vitreous surgery. We review 72 cases of metastatic endophthalmitis from the past decade, including five not previously published. The spectrum of causative bacteria changed significantly during this period, with displacement of meningococcus by Bacillus cereus as the most frequently reported agent and an increasing incidence of infection by organisms of low pathogenicity in immunologically compromised hosts. We propose a new classification scheme for metastatic endophthalmitis based on the location (anterior or posterior segment) and extent (focal or diffuse) of the primary intraocular infection. Focal and anterior cases appear to have a good prognosis, while posterior diffuse disease nearly always leads to blindness. Our analysis of outcomes suggests that systemic antibiotics are more valuable in metastatic than in postoperative or traumatic endophthalmitis and that intraocular antibiotic injection and vitrectomy make only a limited contribution to successful treatment in metastatic infection. We recommend a clinical approach to metastatic endophthalmitis that minimizes exposure of patients to the risks of invasive procedures.

Adolescent↗