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Biomedical subjects

L Galligani

Publications and source records attributed to L Galligani.

8 recordsLinked to original sources
PubMed1992

[Prevention of hepatitis B infection in the neonatal care section of the Biella Hospital during a 5-year period from 1986 to 1991. Results and conclusions].

The paper reports the passive and/or active prophylaxis against hepatitis B virus infection carried out in the Neonatal Section of Biella Hospital during the 5-year period 1986-1991. All neonates and non-neonatal subjects at risk of vertical and/or horizontal contagion were vaccinated. The aim of this study was to compare the levels of compliance in relation to serum controls during pregnancy, acceptance of vaccination, percentages of seroconversion and collateral effects. In conclusion, the author underlines the good compliance both during screening in pregnancy and in accepting vaccination. The percentages of seroconversion were similar to those reported in the literature, as was the incidence of HBsAg-positive pregnant women in the local population. Complications were virtually nil both in relation to incidence and severity.

Female↗
PubMed1992

[Intrauterine torsion of the spermatic cord].

Description of a clinical case diagnosed in the first hours of life in apparently well newborn. Diagnostic suspicion by palpation and transillumination. Absence of any subjective sign. Inspective symptom the light scrotal swelling. The neonate received an immediate surgical exploration with subsequent orchiectomy.

Genital Diseases, Male↗
PubMed1979

Collagen metabolism in the liver of normal and carbon tetrachloride treated rats.

A significant increase in the activity of prolyl hydroxylase, in the relative collagen synthesis and in the hydroxyproline content was observed in the liver of rats treated for five weeks with CCl4 when compared to control liver. Five weeks after the suspension of the treatment, the activity of prolyl hydroxylase and the relative collagen synthesis returned to normal, but the hydroxyproline content of the liver of the CCl4-treated animals remained significantly higher than that of the controls. These findings suggest that an impairment in the mechanisms responsible for the resorption of the scar tissue could account for the accumulation of collagen within the parenchyma in liver fibrosis.

Animals↗
PubMed1978

Interactions between different corneal proteoglycans.

Proteoglycans were extracted from bovine cornea with 4M-guanidinium chloride and purified by CsCl-density-gradient centrifugation. Under associative conditions two fractions were found: one capable of forming assemblies of high molecular weight and another lacking this property. The heavier fraction (density 1.59 g/ml) was eluted as a single retarded peak from Sepharose 2B, but on DEAE-Sephadex chromatography, gave two peaks: the first (eluted with 0.75 M-NaCl) contained mainly proteochondroitin sulphate and the second (eluted with 1.25 M-NaCl) mainly proteokeratan sulphate. Each of these proteoglycans was more retarded on Sepharose 2B than was the original sample from density-gradient centrifugation. Re-aggregation was obtained by recombination of the two fractions. The lighter fraction (density 1.44 g/ml), containing predominantly keratan sulphate chains, was eluted from DEAE-Sephadex as a single peak with 1.25 M-NaCl and was retarded on Sepharose 2B: this fraction was not able to form aggregates with proteochondroitin sulphate. Chemical analyses of the carbohydrate and protein moieties of the proteoglycans from DEAE-Sephadex confirmed that, in the cornea, different subunits are present with characteristic aggregation properties and hydrodynamic volumes.

Animals↗
PubMed1977

[A case of Ehlers-Danlos syndrome].

A case of Ehlers-Danlos syndrome, personally observed, is described. Stress is laid on the rarity of this syndrome (less than 200 cases in the world literature) and on its peculiar symptoms. The familial character of this syndrome was not proved in the case observed.

Capillary Fragility↗
PubMed1975

Stimulation of synthesis of free chondroitin sulfate chains by beta-D-xylosides in cultured cells.

Beta-Xylosides stimulate 2- to 6-fold the synthesis of glycosaminoglycans by three types of nonconnective tissue cells (RG-C6, NB41A, and rat hepatoma cells, and normal and simian virus 40 (SV40)-transformed normal human skin fibroblasts. The effect, which is specific for the anomeric linkage and the glycone, is observed in the presence and absence of puromycin. Beta-Xylosides may substitute for xylosylated core protein as initiators of synthesis of chondroitin sulfate chains. No stimulation of synthesis of heparan sulfate was observed. With the use of a fluorogenic xyloside, 4-methylumbelliferyl-beta-D-xyloside, it was demonstrated that the free chondroitin sulfate chains secreted into the medium bear the xyloside at the reducing end, and have an average molecular weight of 16,500.

Animals↗