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Biomedical subjects

L Gasbarre

Publications and source records attributed to L Gasbarre.

3 recordsLinked to original sources
PubMed1997

Distractibility and symptoms in schizophrenia.

Distractibility was assessed in 59 inpatients with a relapse of schizophrenia and 3 mo later during a period of relative remission. Distractibility was measured with a digit span task and symptoms with the Positive and Negative Syndrome Scale (PANSS). Although positive and negative symptoms improved significantly, the schizophrenia subjects' performance on the digit span task remained stable over time. There was no relationship between attention and symptoms. The possibility of distractibility being a vulnerability indicator for schizophrenia is discussed.

Adult↗
PubMed1984

Kinetics of immunoglobulin and specific antibody responses of CBA mice infected with Trypanosoma rhodesiense.

Groups of CBA/CaJ and B-cell deficient CBA/N mice were infected with Trypanosoma rhodesiense EATRO 1886 strain. Survival, parasitaemia, serum Ig levels plus specific trypanosomal IgM and IgG antibodies were assayed and compared during infection. Whereas both strains of mice had similar parasitaemias during the first week of infection, CBA/N parasitaemias were lower than those observed in CBA/CaJ mice during the subsequent study period. Antibody responses, specific for T. rhodesience antigens, peaked on day 10 after infection in CBA/CaJ mice, then rapidly declined. However, antibody responses in CBA/N mice remained elevated throughout the study. In addition, the kinetics of specific IgG and IgM varied in CBA/N mice: IgG antibody was detected on day 4, whereas specific IgM was detected on day 16. This unique relationship between the appearance of IgG and IgM antibody may explain the longer survival observed for B-cell deficient CBA/N mice infected with T. rhodesience.

Animals↗