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Biomedical subjects
Publications and source records attributed to L Gavriliţă.
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A case of amyloid tumor of the palate is reported in a 10-year-old girl. The past history, the detailed general clinical and laboratory examinations, and biopsy specimens collected from the rectal mucosa, gingiva, tongue, and skin excluded other forms of localizations of amyloidosis. The isolated amyloid tumor is an exceptional form of amyloidosis, and in the available literature we have not found mention of its localization on the palate.
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There is much controversy regarding the chronic nonspecific duodenitis as autonomous clinical entity. We have studied 36 patients (16 women, 20 men), aged 24-59 years (mean age 37.8 years), with biliary dyspepsia and endoscopic changes suggesting "duodenitis"; in all patients the following investigations were carried out: gastric secretion, barium X-ray and histological examination of the duodenal mucosa specimens obtained by endoscopic biopsy. There was no significant difference between the patients with duodenitis and normal subjects regarding the maximal acid output. Unspecific radiological changes were noticed in 55.5% of patients with chronic duodenitis. Endoscopy showed varied changes of duodenal mucosa including edema, erythema, erosions and hypertrophic folds. Histology confirmed the presence of inflammation. The patients have been followed-up for three years and none of them developed duodenal ulcer. We conclude that chronic nonspecific duodenitis is an autonomous clinical entity.
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Electron microscopic researches pointed out the existence of amphicrine cells in the peritumoral mucosa on specimens of surgically resected gastric cancer. According to the ultrastructural features two cell subtypes were distinguished: mucoenterochromaffine (EC1, EC2) and empty clear mucoforming cells, corresponding to the mucoargentaffine and mucoargyrophobic types, respectively as the literature showed. Our results showed the amphicrine cells may be interpreted as transformed pathological endocrine cells under gastric cancer conditions.
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