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Biomedical subjects

L Georgescu

Publications and source records attributed to L Georgescu.

15 recordsLinked to original sources
PubMed1976

[Fibrosarcoma of the orbit (author's transl)].

During a period of 8 months a capsulated orbital tumour--not adherent the orbital walls or the bulbus--developed in a 21-year-old female patient. The tumour was exstirpated in toto. The histological findings show a fibrosarcoma with poorly differentiated cells, giant cells and numerous mitoses. The comparatively small incidence of the tumour as well as the prognosis quoad vitam are discussed.

Adult↗
PubMed1975

Cardiac tumour in infant.

A case of an eighteen-month-old-infant who died in narcosis following an aortic obstruction by myxomatous tumour of the left ventricle is reported. Since his birth the infant exhibited cyanosis fits and cerebral manifestations due to an intermittent occlusion of the aorta. The result of the post-mortem examination pleads for including the cardiac myxoma amongst the true tumours.

Aortic Diseases↗
PubMed1975

The role of capillary wall in the histogenesis of glomerular diseases.

The glomerular capillary is the most solicited renal component of the local and general systems of integration both under normal and pathological conditions. The alterative and reactive modifications of the glomerular capillary may be the expression of a systematic capillary disease of the initial involvement of ths structure of glomerular corpuscles. The sum of certain kind of lesions of the complex glomerular structure realizes diverse morphofunctional entities of proliferative, membranous, and sclerocicatricial glomerular diseases. The glomerular diseases, irrespective of their nature, induce changes in the balance of the intra-and internephronal relationships, realizing new vicious circles which amplify and maintain the tissular destructions.

Capillaries↗
PubMedDate not supplied

Balkan nephritis. A synthetic view on 50 studied cases.

Epidemiological, clinical pathological investigations concerning Balkan nephritis (BN) have revealed some particular aspects which define this condition as a distinct nosologic entity. Its endemic familial character and its occurrence restricted to some limited geographic areas in Bulgaria, Yugoslavia and Romania, are highly unusual. BN leads to chronic impairment of the renal function which is, however, not constantly associated with edema and hypertension. The duration of the disease is prolonged; death takes place from uremia within five to ten years. Gross pathologic changes are consisting of severe bilateral atrophy of the kidneys, with structural changes suggesting a 'renal cirrhosis'. The etiology of the disease is obscure. Investigations carried out by means of electron microscopy and immunofluorescence tests are suggesting that the pathogenesis is rather complex. The role of a persistent tolerated or slow, latent virus infection in certain families, that of some toxic factors, and the implication of autoimmune mechanisms are to be considered.

Bulgaria↗
PubMedDate not supplied

[Mechanism of production of porcelain gallbladder].

An observation is presented, of a case, of particular demonstrative value, of "porcelain gall-bladder", in which the authors were able to evidence the intervention of three local pathogenic factors: chronic inclavation of a stone in the bladder neck and obliteration of the cystic duct (which eliminated from the physiological viewpoint the gall-bladder); a chronic inflammation of the wall and ischaemia of the entire organ following the previous obliteration of the cystic artery. These factors are only in exceptional circumstances met in the same patient and this explains the rarity of this complication of biliary lithiasis.

Calcinosis↗
PubMedDate not supplied

Trichinous nephropathy.

Lesions of glomerular nephropathy were found in 5 cases of acute trichinosis, characterized by a low proteinuria and hematuria as well as by moderate deficit of the renal function. Renal biopsy revealed lesions of proliferative glomerulitis, while immunofluorescence examination showed granular deposits of IgG and beta1-C-globulin on basement membranes. Serum complement was reduced. These observations suggest an immunological mechanism in the development of the glomerular nephropathy during acute trichinosis.

Acute Disease↗