[Treatment of depression. Comparative study on the effects of mianserin (Tolvin) and amitriptyline].
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Biomedical subjects
Publications and source records attributed to L Ginman.
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The results of double-blind comparative trials carried out simultaneously in three Finnish hospitals are presented. The antidepressant activity and side-effects of mianserine (ORG GB 94) and amitriptyline were compared. No statistically significant differences were found between the two treatments. It was found, however, that mianserine had clearly less anticholinergic side-effects than amitriptyline.
One hundred patients who in 1963 had attempted self-poisoning and were subsequently admitted to the intoxication ward of a psychiatric hospital were studied twice: immediately after the attempted self-poisoning and 8 years after the attempt. It was found that within the follow-up period a total of nine patients had died, four of whom had committed suicide. The risk of suicide per years is .5%. According to the literature the range of the annual suicide risk is .9% to 2.5%.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.