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L Guglielmi

Publications and source records attributed to L Guglielmi.

30 records · Page 2Linked to original sources
PubMed1976

Stabilization of double-stranded DNA molecule by non-histone peptidic effector from calf thymus.

A peptidic effector from calf thymus causes a strong stabilization of DNA double-stranded molecule in vitro. The active factor was isolated from aqueous ultrafiltered thymus extracts and purified by means of chromatography on DEAE-cellulose and then on Dowex 50 WX2. The purified thymic factor was characterized as a peptide of low molecular weight (less than 5000). The biological activity of the thymic factor cannot be attributed to a histone fragment. Melting data of the control DNA and of the DNA-active factor complex in various conditions of ionic strength and dielectric constant of the solution medium are recorded.

Animals↗
PubMed1975

Evidence for the presence in calf thymus of a peptidic factor controlling DNA transcription in vitro.

A thymic factor causes a strong inhibition of the DNA-directed RNA polymerase reaction in vitro. The active factor was isolated from aqueous ultrafiltered thymus extracts and purified by means of chromatography on DEAE-cellulose and then on Dowex 50 WX2. The purified thymic factor was characterized as a peptide of low molecular weight (less than 5000). The biological activity of the thymic factor cannot be attributed to the presence of a nuclease or of a histone fragment. The RNA synthesis is controlled by this factor by means of electrostatic interactions between the peptide compound and DNA. Inhibitory activity on RNA synthesis was absent from kidney extracts.

Animals↗
PubMedDate not supplied

[The organization of a working group for the prevention of decubitus lesions].

The authors report the results of a two years monitoring program focused on patients at risk of and with bedsores in the general hospital of Castelfranco Veneto. The purpose of the multidisciplinary exercise (which saw the participation of nurses, pharmacists, doctors) was the activation and the evaluation of treatment protocols. The overall recruited sample included 679 patients, with a prevalence of 61% of lesions at the occasion of the first observation, and of 57% in the last one. The hardly quantitatively different prevalence is better understood from a qualitative point of view: the number of lesions per patients drops slightly from 1.9 to 1.7; one out of four of the "at risk" patients became "at no risk"; a 30% improvement is observed with respect to treatment efficacy. It is suggested that a positive effect may be obtained through a sustained attention to the problem and the careful definition of the interventions to be planned.

Humans↗
PubMedDate not supplied

[The body and its meanings].

The human body is the natural object of studies, analyses and care in the health field. The Authors, starting from this remark and taking the body language and its meaning into consideration, point out that the body contact allows either to deliver an adequate nursing care or to take off dignity and humanity. A concise review of the human body significance during the course of history makes us aware that, as a matter of fact, the different and opposite conceptions that followed one another haven't made the concept of body definitively clear. Inside the care field, the knowledge and use of the body language--complementary to the verbal one--assumes many different meanings, that can condition the relation process in a substantial way.

Body Image↗