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L H Ling

Publications and source records attributed to L H Ling.

41 records · Page 3Linked to original sources
PubMed1988

[Chromosome of transplantable lung adenocarcinoma cell line (LA-795)].

The chromosome patterns of lung adenocarcinoma cell line LA-795 were studied with G and C banding techniques at passages 60 and 100. The model chromosome numbers were 69, 68, 67 and 66. G banding of 46 cells of the four clones (69, 68, 67 and 66) were analysed. The chromosome patterns of this cell line were hypotetraploid male cells which were similar to those transplanted in mice. The 69 model chromosome comprises two types, 69I and 69II. According to the karyotype analysis, the evolution process of clone from 69 to 68, 67 and 66 was recognized by the karyotype of various clones. The lose of chromosome No. 4 and No. 14 in various model chromosome cell lines may be a non-random chromosome aberration of mouse tumor cells.

Adenocarcinoma↗
PubMed1985

[The G and C banding chromosome patterns of the transplantable mammary adenocarcinoma in mice].

Cells of mice MA-737 mammary adenocarcinoma from 5 different generations were analysed by G and C banding techniques. Altogether, 540 metaphase plates were studied. All chromosomes showed telocentric and C bands. The modal chromosome numbers were 41, 82, 86, 89 and 91. The karyotype of cells with 41 modal number was 41, XO, +7 +M. In most of the cells, one or two marker chromosomes were present. This marker is characteristic of all MA-737 cells. The relationship between chromosome aberration and malignant transformation is briefly discussed.

Adenocarcinoma↗