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Biomedical subjects

L H Stocks

Publications and source records attributed to L H Stocks.

6 recordsLinked to original sources

Popliteal artery aneurysms. Past and present.

Popliteal artery aneurysms have had an important historic role in the development of modern vascular surgery. Early methods of surgical therapy for these aneurysms are detailed in this report for a persepctive. Clinical aspects of surgical diagnosis and treatment of 35 popliteal artery aneurysms in 26 patients are also reviewed. Such aneurysms often present with varied symptoms and should be considered a treacherous disease entity since limb loss occurs in a considerable number of patients. Coexisting disease frequently complicates both the intraoperative and postoperative course of these patients. In this series of popliteal aneurysms, excision and venous autograft interposition offered the most successful operative therapy.

Aneurysm

Inflammatory carcinoma of the breast.

Inflammatory carcinoma of the breast was found in 30 of 1,458 patients with carcinoma of the breast seen at this medical center during a 20 year period from 1951 to 1971. These patients were evaluated for predisposing factors, presenting symptoms, physical characteristics and histologic findings. No single mode of therapy produced more than a rare five year survival period. Radical surgical procedures are seldom indicated.

Adult

Management of recurrent melanoma of the extremity.

Two forms of therapy employed for treatment of patients with recurrent melanoma limited to the extremity, and carried out during different intervals of time, are presented. Perfusion of the involved extremity with phenylalanine mustard has resulted in a 5-year survival rate of 28% of 43 patients. A second group of 25 patients has been treated by a four-stage immunotherapy program consisting of sensitization with intradermal BCG, followed in 6 weeks by intra tumor injection of BCG. A third stage involved the activation of the patients's lymphocytes, after removal by a blood cell separator, incubated in vitro with irradiated neuraminidase-treated melanoma cells and reintroduced into the patient either by subcutaneous or intratumor injection. The fourth stage of immunotherapy involves injection of an inoculum of irradiated neuraminidase-treated autochothonous tumor cells plus BCG injected intratumorally or subcutaneously. Sixteen of 24 patients receiving immunotherapy treatment program have experienced arrest of their disease lasting from 5 to 42 months.

Adult