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Biomedical subjects

L Handler

Publications and source records attributed to L Handler.

30 records · Page 2Linked to original sources
PubMed1979

Agnogenic myeloid metaplasia and spinal cord compression.

A 55-year-old White male with agnogenic myeloid metaplasia, proved on bone marrow trephine biopsy, underwent splenectomy for abdominal discomfort. Six months later he developed paraparesis and on myelography multiple extradural obstructions were seen. In the absence of other obvious diagnostic possibilities, these were attributed to areas of extramedullary haematopoiesis, and he was treated with local radiotherapy. However, the neurological deficit progressed and emergency laminectomy and decompression were undertaken. Tissue obtained at this time confirmed the diagnosis of agnogenic myeloid metaplasia. A repeat myelogram showed complete relief of the obstruction, but the patient developed fulminating septicaemia and died. These findings are reported in view of the great rarity of spinal cord compression due to multiple areas of extramedullary haematopoiesis.

Humans↗
PubMed1977

Personality and background predictors of a young wife's desired family size.

A questionnaire that included 19 personality, socioeconomic, and general background variables was administered to 160 childless Caucasian, Protestant wives of college students to discover variables that offered promise as predictors of desired family size. Of the samples, 66% wanted two children, and 14% wanted three children. Four variables--feelings of alienation, father's social class level, level of overt anxiety, and childhood family size--had a combined multiple correlation of .39 with desired family size in a stepwise regression analysis and accounted for almost 15% of the desired family size variance. Results suggest that although desired family size remains difficult to predict, personality factors may be as significant as socioeconomic factors in its prediction.

Age Factors↗
PubMedDate not supplied

Leigh disease (subacute necrotizing encephalomyelopathy): MR documentation of the evolution of an acute attack.

The radiologic evolution of Leigh disease is documented with sequential brain MR in the acute phase of the illness, at 3 weeks, and at 3 months. High-signal-intensity lesions seen on T2-weighted images in the first week resolved by 3 months, whereas new lesions appear during the chronic stage. Putamenal involvement is not a pathognomonic radiologic finding. Brain stem tegmentum, particularly the mesencephalon, is characteristically involved on MR in the early and late phases of the illness.

Acute Disease↗