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Biomedical subjects

L Hartling

Publications and source records attributed to L Hartling.

13 recordsLinked to original sources
PubMed1997

A population-based study of hospitalized injuries in Kingston, Ontario, identified via the Canadian Hospitals Injury Reporting and Prevention Program.

This report uses data from the Kingston and Region Injury Surveillance Program (KRISP), a subset of the Canadian Hospitals Injury Reporting and Prevention Program (CHIRPP), to describe rates and identify patterns of hospitalized injury in Kingston and area. During 1994 and 1995, there were 998 reported hospitalizations for injury, resulting in an overall rate of 30.0 injuries per 10,000 per year (males: 30.3 per 10,000; females: 29.7 per 10,000). Major patterns of hospitalized injury were identified as priorities for intervention: 1) falls in all age groups, but especially those in children, and falls leading to hip and pelvic fractures among older adults, the majority of which occurred in residential settings; 2) motor vehicle and other transport injuries (e.g. motorcycle injuries) in all age groups; and 3) intentional injuries (e.g. fights) among males aged 20 64 years. Discussion focuses on the use of the surveillance system to set priorities for prevention and further research within this population.

Accidental Falls↗
PubMed1987

The effect of the tricyclic antidepressant drug, nortriptyline on left ventricular ejection fraction and left ventricular volumes.

Eight patients with major depression but otherwise healthy underwent radionuclide cardiography before and during nortriptyline treatment. The second examination was performed when the nortriptyline plasma concentration was within the therapeutic range (60-150 micrograms X l-1). Heart rate, arterial blood pressure, left ventricular ejection fraction, left ventricular volumes, systolic pressure-volume ratio, and cardiac output were determined. Heart rate increased in mean by 13% (P less than 0.05). All other variables were unchanged. We conclude that nortriptyline in therapeutic doses produces no major adverse effect on left ventricular function. Routine radionuclide cardiography might be a suitable method to detect among those treated with tricyclic antidepressants the occasional susceptible patient. This may particularly apply to patients with known heart disease and to elderly patients.

Adult↗
PubMed1984

Nicholson score for prescribing digoxin compared with Jellife nomogram.

A series of 84 medical inpatients were treated in random order with oral digoxin in doses calculated according to the newly introduced Nicholson score and the Jellife formula and nomogram. The daily dose of digoxin was lower (p less than 0.01) according to the Nicholson score (mean 2.1 digoxin tablets of 62.5 micrograms daily). The mean serum concentration of digoxin was also lower (p less than 0.01) according to the Nicholson score (1.27 nmol/l) than according to the Jellife nomogram (1.84 nmol/l). Estimated by the Nicholson score the serum concentration of digoxin was not optimal (p less than 0.01) and not within an acceptable therapeutic range (p less than 0.01) in more patients than when estimated by the Jellife nomogram. It is concluded that the Nicholson score is not suitable for medical inpatients.

Aged↗
PubMed1983

The day-to-day variation in serum digoxin concentration. The Hørsholm digoxin study.

Serum digoxin concentration was measured in 70 medical patients 7 and 8 days after admission to hospital. The digoxin treatment taken at home was continued in hospital. There was no statistically significant difference between mean digoxin concentrations in samples taken at day 7 (1.52 nmol/l) and day 8 (1.48 nmol/l). The variation in serum digoxin concentration from day to day expressed as SD was 0.25 nmol/l; 95% confidence limits were +/- 0.51 nmol/l, and 99% confidence limits +/- 0.67 nmol/l. Variations in serum digoxin concentration were not correlated to age, sex, body weight, serum creatinine and the oral dose of digoxin.

Aged↗