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Biomedical subjects

L Hassler

Publications and source records attributed to L Hassler.

4 recordsLinked to original sources
PubMed1985

[Parenteral nutrition in postoperative gastrointestinal fistulas].

During 1981-1984 13 patients with clinically manifest postoperative fistulas (11 small intestinal and 2 colonic) were treated with parenteral hyperalimentation. The therapy only ensued on intensive care conditions and a spontaneous closure of the fistula was observed in 7 patients, in 2 patients closure ensued after relaparotomy and parenteral hyperalimentation the time before. Time of therapy was 18 days on an average, the amount of calories was 2,900-3,400 kcal/day.

Adolescent↗
PubMed1976

Acetylator phenotype in patients with hydralazine-induced lupoid syndrome.

The acteylator phenotype has been determined (isoniazid half-life) in 31 patients, 25 of them women, who had exhibited a lupus erythematosus-like syndrome during treatment with hydralazine. Twenty-nine patients were slow acetylators, one was rapid (probably spontaneous SLE) and one uncertain. Only two patients had been given more than 200 mg of hydralazine daily. The mean duration of therapy was 32 months at the onset of symtoms. These were not serious but rather long-standing. Our study confirms that patients who risk developing hydralazine lupus are slow acetylators, especially females, treated with more than 100 mg daily. Rapid acetylators seem to develop this side-effect rarely, if at all.

Acetylation↗