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Biomedical subjects

L Heuser

Publications and source records attributed to L Heuser.

At least 91 records · Page 5Linked to original sources
PubMed1980

[The value of computer tomography and sonography in the investigation of the pancreas (author's transl)].

Three hundred and five patients were examined by computer tomography and sonography. In 117 patients no abnormalities were found in the pancreas. The accuracy of computer tomography was 87%, of sonography 85%. In 41 patients the presence of a carcinoma of the pancreas was confirmed histologically. In this group the sensitivity of computer tomography was 83%, of sonography 85%. Thirty-four patients suffered from acute pancreatitis. In this group sensitivity of the two methods was equal at 79%. 113 patients had changes of chronic pancreatitis. Sensitivity of computer tomography was 84%, of sonography 70%. Computer tomography is better at demonstrating calcification in the pancreas. Atrophy of the pancreas cannot be diagnosed by sonography.

Acute Disease↗
PubMed1980

[CT scanning of the kidneys--efficiency and diagnostic value (author's transl)].

Shorter scan times have been shown to improve image quality in Computerized Tomography. With the help of bolus injected contrast medium blood vessels and well vascularized structures in the kidneys can be visualized. In this report normal anatomy and pathological changes of the kidneys are described and demonstrated. CT was found to be a reliable method in diagnosis of various kidney diseases especially involving space occupying lesions, and it reduces the need of invasive techniques such as angiography. Nevertheless intravenous urogramm should be the initial examination in kidney disorders.

Adenocarcinoma↗
PubMed1979

[Computed axial tomography (cat) in the diagnosis of diseases of the heart and aorta (author's transl)].

Computed axial tomography (CAT) was used in 70 patients with diagnostic problems centering on the heart (47 patients) or the aorta (23). The method proved suitable for the diagnosis, differential diagnosis and serial control of pericardial effusions and also well demonstrated intracardiac tumours. Aortic aneurysms are also easily demonstrated and their extent can be exactly defined. But aortic wall dissection and stenosis of arteries arising from the aorta are not visualized and therefore require angiography.

Adolescent↗
PubMed1979

Relation between mammary cancer growth kinetics and the intervals between screenings.

The purpose of this study was to consider the time interval for periodic mammographic screening for breast cancer. One hundred fifteen breast cancers occurring in 10,128 women receiving over 30,000 mammograms over a four year period were reviewed. Tumors were diagnosed at three time intervals: 1) first screening (39/115); 2) annual examination (27/115); and 3) at an examination that occurred less than twelve months from a previous annual examination (10/115). Also, there were tumors that grew to a palpable dimensions and were self-detected between annual examinations (39/115). Our opinion is that screening intervals should be individualized to each patient according to risk factors and suspicious mammographic findings. Further, there is a significant number of breast cancers that grow too fast to be detected effectively by annual mammography. Suspicious mammographic findings did not exist before these cancers reached palpable dimensions. Other risk factors characterizing the hosts who develop these fast growing cancers are yet to be determined.

Biopsy↗
PubMed1979

Growth rates of primary breast cancers.

The growth rates of breast cancers are a critical aspect of the natural history of the disease. Growth rates of 32 primary breast cancers were determined from serial mammographic views of tumor nucleus shadows in a population of 109 cancers. These cancers were found in a screening population of 10,120 women receiving over 30,000 mammograms over 3 years. Tumor volume doubling times ranged from 109 days to 944 days with mean doubling time of 325 days in 23 cases with 9 tumors showing no growth. Additional cancers surfaced that were growing too fast to be measured. These cancers were significantly more likely to metastasize but because of the small sample size the absolute percentage of tumors in that fast growing subset was not determinable but ranged between 17 and 77% of the 109 cancers.

Breast Neoplasms↗
PubMed1979

[Positive ventriculography and computer assisted tomography of the skull in the evaluation of megalocephaly in newborns and infants (author's transl)].

To clarify indications and limits of computer assisted tomography and positive ventriculography the results of both methods were compared with each other retrospectively in 55 macrocephalic newborns and infants. It could be shown that positive ventriculography, even if combined with coronal views, was superseded by computer assisted tomography to only a certain extent. To complete the appropriate diagnosis preoperatively positive ventriculography was necessary most often in patients with paranatal disturbances who had undergone intensive care treatment. The non-invasive method of computer assisted tomography often yielded sufficient information on localisation, size, and nature of the underlying pathologic process. Both methods turned out to be complementary when topographical and functional interrelations of cranial cysts had to be demonstrated, especially structures of the midline and of the posterior fossa, which could not be visualized by computer assisted tomography alone.

Brain Neoplasms↗
PubMed1979

[Extension of thoracic roentgen diagnosis by computer tomography (author's transl)].

In 400 examinations of the thorax results of computer tomography were compared with respective pa chest films and conbentional tomograms. In the peripheral areas of the lung, interstitial parenchymal alterations and metastases were better visualized by CT. The size of central bronchial carcinomas and space-occupying lesions of the thoracic wall can be determined with greater accuracy by CT. Primary tumors, lymphnode enlargement and vascular alterations can be differentiated and localized more precisely by CT. The size of the heart chambers, intracavitary tumors as well as septal and myocardial wall thickness can be determined non invasively.

Aortic Aneurysm↗
PubMed1979

The association of pyloric antral tissue levels of 5-hydroxytryptamine and restraint stress ulceration in the rat.

To determine the possible role of 5-hydroxytryptamine (5-HT) in the formation of restraint ulcerations, we investigated the relationship among mucosal tissue levels of 5-HT, vagotomy, and restraint ulcerations. Three murine experimental groups and one control group were used to compare the ulcerogenic effects of restraint with and without prior vagotomy. Ulcers were graded as to frequency, size, and hemorrhage on a 0-4+ scale. 5HT was measured in the gastric mucosa of each animal. Restraint caused significant ulcerations. The mean tissue level of 5-HT was significantly higher in the group with marked ulcerations (p less than 0.001). Our data suggest an increased cellular production of 5-HT during the development of the restraint ulcers. Vagotomy protected the animals against restraint ulcerations without depleting the baseline levels of 5-HT. Previous experiments have shown that urine levels of 5-hydroxyindoleacetic acid (5-HIAA) increase during the restraint period. Thus, increased tissue and urine levels of 5-HT appear to coincide with the development of restraint stress ulcers in the rat. Accordingly, if the coincidence occurs in humans, the measurement of urinary levels of 5-HIAA may be an indirect means of determining those patients at high risk for the development of stress ulcers.

Animals↗
PubMed1978

[Computer cardio-tomography for tumours of the left atrium (author's transl)].

The role of computer tomography in the diagnosis of cardiac tumours was demonstrated by three patients with myxomas of the left atrium. After intravenous contrast administration these tumours appeared as relatively translucent space-occupying lesions on the computer tomograph. The invasive method of angio-cardiography is unlikely to provide any additional information concerning tumour size or localisation when compared with non-invasive computer tomography or echo cardiography.

Female↗
PubMed1978

[Diagnostic relevance of computer tomography (CT) in pancreatic disease (author's transl)].

CT-x-ray examination of 98 patients yielded pathologic results in 42 patients; in 33 patients results of CT could be controlled by surgery or at autopsy. In 14 cases necrotizing pancreatitis or pancreatic pseudocysts were suspected and these cases were operated upon; only 1 case turned out to be a falsely positive diagnosis. In 15 cases pancreatic carcinoma were found at surgery; 13 of these cases had been diagnosed preoperatively by CT; the diameters of the 2 tumors not diagnosed were below 3-4 cm. Differentiation between cysts, pancreatitis and tumors was possible in 2/3 of all cases; in 1/3 of the cases differentiation was neither possible by applying morphological criteria nor by evaluating absorption spectra. It turned out to be advantageous to examine the parenchymatous organs surrounding the pancreas by CT as well; in about 12% of cases with pathological findings the processes were found to be localized extrapancreatically.

False Positive Reactions↗
PubMed1978

[Extension of thoracal diagnostics through computer tomography (author's transl)].

The utilization of transverse layers in computer tomography opens up a new level of examination for localization of pathologic processes in the thorax and their spread. The good resolution of roentgen absorption differences in the soft parts enables the use of computer tomography in the diagnosis of pericardial effusions and for further differentiation of known mediastinal growing and displacing processes. This method is also suitable for the identification of aneurysms, since it is not invasive and places hardly any strain on the patient. Finally, computer tomography can also be used for radiotherapy and operation planning, as well as in target biopsy on account of the true-to-scale and reproducible image of the body cross-sections.

Aortic Diseases↗
PubMed1978

[The efficiency of computer-tomography and conventional tomography of processes of the skull and of the skullbase (author's transl)].

In 12 patients with tumorous or chronic-inflammatory diseases of the skull and the skullbase the results of conventional and computer-tomography were compared with the operative findings. The computer-tomography of the most important regions is demonstrated by individual examples. The preliminary results indicate, that computer-tomography is reliable in evaluation of the extend of pathological processes. Therefor follow-up data after treatment were obtained by computer-tomography only.

Carcinoma↗
PubMed1978

[Diagnosis of aortic aneurysms by computerized tomography (author's transl)].

Computerized tomography has proved to be of great value in the assessment of aortic aneurysms; since it provides all necessary information about length, width, intraluminal thrombi, and calcification of the wall. Especially in cases of ruptured aneurysms the hemorrhage and its extent to retroperitoneal and intraperitoneal space can be well demonstrated.

Aged↗