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L Hidalgo

Publications and source records attributed to L Hidalgo.

At least 37 records · Page 2Linked to original sources
PubMed1990

[Is it necessary to combine the surgical treatment of kidney adenocarcinoma with ipsilateral adrenalectomy?].

We analyzed a series of 202 renal adenocarcinomas, 164 of which were submitted to radical nephrectomy. Pathological analyses of 150 adrenal glands revealed ipsilateral adrenal metastasis in 4 cases, 3 of these coexisting with other distant metastases. The primary tumors in these 4 cases were highly undifferentiated and in the advanced local tumor stage; the only case with solitary adrenal metastasis survived 15 months. The present study and data reported in the literature indicate that ipsilateral adrenalectomy should be performed in addition to radical nephrectomy only in renal tumors of the upper pole, those localized at other sites but whose size indicate the possibility of tumor spreading to the adjacent adrenal gland, or when a suspicious mass in the adrenal gland is evidenced by the preliminary workup or during surgery.

Adenocarcinoma↗
PubMed1990

[Kaposi's sarcoma in kidney transplant treated with cyclosporin and azathioprine].

We report on a renal transplant patient who had developed Kaposi's sarcoma with cutaneous involvement 20 days after transplantation. The patient had a functioning renal graft and was on immunosuppressive therapy consisting of prednisone, azathioprine and cyclosporine. Azathioprine and cyclosporine were discontinued and chemotherapy was instituted with vinblastine first and methotrexate later; however, Kaposi's tumor did not respond to the foregoing therapeutic regimen. Thirty-two months following transplantation, the kidney graft presented acute interstitial rejection that warranted graft removal. The patient is currently receiving treatment for Kaposi's sarcoma but tumor regression has not been achieved. We discuss the atypical course of this case in comparison with those reported elsewhere.

Azathioprine↗
PubMed1989

[Oat cell carcinoma of the esophagus].

Extrapulmonary locations of undifferentiated small cell carcinoma of the "oat cell" type are uncommon. In spite of its rarity, the appearance of this type of tumor has been described in various organs of the economy. Of these, the esophagus is the most common location, constituting 0.05 to 7.6% of esophageal carcinomas. Of uncertain histopathologic origin, these tumors are characterized by their extreme aggressiveness, which carries a poor short term prognosis. Surgery, radiotherapy and chemotherapy, separately or in combination, have produced discouraging results in the treatment of primitive esophageal "oat cell" carcinoma. In this paper are presented four cases of esophageal "oat cell" carcinoma treated in the Hospital de la Santa Cruz y San Pablo in 1979-1988, out of a total of 260 carcinomas in the same location. The clinical evolution and pathological findings of this type of tumor are commented. The literature on this unusual histological type of carcinoma is reviewed.

Aged↗
PubMed1986

Idiopathic peritesticular fibrosis associated with retroperitoneal fibrosis.

A 32-year-old male who presented with idiopathic retroperitoneal fibrosis developed peritesticular fibrosis 4 years later. The lesion appeared as a diffuse, uniform thickening without a tendency to form nodules. Histologic examination revealed a densely collagenized tissue with scattered cells, consisting mainly of fibroblasts and plasma cells. Small blood and lymphatic vessels of the tumor showed luminal dilation and perivascular edema with inflammatory infiltrates. No other associated pathology was found in the patient. We suggest that peritesticular fibrosis in this patient may be due to lymphatic drainage obstruction caused by retroperitoneal fibrosis.

Adult↗
PubMed1977

Fluorescence urinary cytology in bladder cancer.

300 patients have been studied by means of a fluorescence exfoliative urinary cytology procedure based on the fluorochromatic properties and the affinity of acridine orange for the nucleic acids. The patients were divided inot two groups: in the first group including 238 cases we tried to establish the correlation between the urinary cytological grade and the histological grade of malignancy on biopsy; the rate of accuracy was approximately 77% for low-grade and approximately 88% for the high-grade tumours. In the second group including 62 cases we studied the value of cytology in predicting recurrences; 38 and 66.6% of the cases with grades IV and V, respectively, developed recurrences thus confirming the necessity of cytologic controls in patients under conservative treatment. The overall rate of accurate cytological diagnosis with this staining method has reached 90%.

Cytodiagnosis↗
PubMed1977

Immunological evaluation in patients with urological cancers.

The immunological competence of 100 patients bearing urological cancers was evaluated by means of skin tests and serum immunoelectrophoresis. Cell-mediated immunodepressions were observed in 93.3% of prostatic cancers, 68.6% of bladder cancers and 38.4% of renal cancers. The immunoglobulin values increased in 80% of prostatic cancers, 31.3% of bladder cancers and in 23% of renal cancers. IgA was elevated in almost all the prostatic growths. In bladder and renal cancers a clear correlation between immunodepression and tumour stage was found. Treatment significantly improved the skin test reactivity in the evaluated patients. Metastases and recurrences occurred more frequently in immunodepressed subjects.

Adenocarcinoma↗
PubMedDate not supplied

[Value of parenteral nutrition in total gastrectomy for cancer. A prospective study].

A prospective study is presented in which the impact of total parenteral nutrition (TNP) was analyzed in a group of 27 patients that underwent total gastrectomy due to gastric carcinoma (TGGC). Patients were randomly divided into two groups: Group I was formed by 15 patients and was treated systematically with TPN during the immediate postoperative period (POTPN). Group II was formed by 12 patients who were treated with conventional serum therapy during the immediate postoperative period. TPN was administered if enteral nutrition was not viable and/or patients presented complications. Both groups were similar regarding age, sex, previous illness, previous nutritional status (Preop PNI) and surgical technique used in GI transit reconstruction. Morbidity and mortality rates, nutritional status (PNI 5 days postop) and mean hospital stay were analyzed in both groups. Likewise, a retrospective comparison was made between the results obtained from this trial and those from a group of 44 patients with gastric carcinoma who underwent TGGC at our hospital a decade earlier and did not received TPN during the immediate postoperative period on a routine basis. When both series and Groups I and II were compared significant differences in mean hospital stay were observed in favor of Group I treated with routine TPN in the immediate postoperative period. There were no differences in the mortality rate when all groups were compared. It was concluded that TPN was useful in patients undergoing TGGC because it reduced postoperative mortality rate, decreased mean hospital stay and showed good cost/effectiveness correlation.

Aged↗
PubMedDate not supplied

[Management of injury of the solitary kidney].

Two cases of renal trauma are described herein. The diagnostic work up revealed the patients had solitary kidney. Trauma was classified as grade 1 and 2 and a conservative approach was adopted. The patient with grade 2 trauma was submitted to surgery one month following treatment. Preservation of the renal unit was achieved in both patients. Patient follow up at 16 years revealed no complications or sequelae from the injury. The diagnostic and therapeutic aspects of renal trauma in patients with solitary kidney are discussed.

Accidents↗