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Biomedical subjects

L Holanová

Publications and source records attributed to L Holanová.

5 recordsLinked to original sources
PubMed1981

Antibody to parainfluenza virus types 1, 2 and 3 in sera and nasal secretions of persons of different age.

Serum and secretory antibody levels against 3 types of parainfluenza virus were determined in persons ranging in age from 1 month to 74 years. With a slight decline in the group of 7 months to 2 years of children, the number of positive findings increased with age, reaching maximum in the groups of 16-24 years [types 1 and 2] and 25-74 years [type 3] old persons. Nasal secretory antibodies against parainfluenza type 3 virus were detected in all age categories, the highest number of positive findings occurred in the group of 16-24 years old persons. Secretory antibodies against type 2 virus were detected also in all age groups, but the number of positive findings was considerably lower. Secretory antibodies against type 1 virus were detectable in persons over 5 years of age, with a maximum in the age category of 16-24 years. The percentage of positive persons with antibody to type 1 virus was the lowest.

Adolescent↗
PubMed1978

Haemagglutination inhibition antibodies in nasal secretions of persons after natural parainfluenza virus infection.

In 7 adults and 7 children with upper respiratory illness of parainfluenza aetiology, the virus was isolated in the acute phase from nasal washings or nasal smears in spite of high titres of haemagglutination inhibition (HI) antibodies in serum. By contrast, secretory HI antibodies were not demonstrated at the onset of illness in any of the patients, but their formation started early and the antibodies reached maximal levels about 10 days after onset of illness. The individual patients showed considerable differences in the dynamics of secretory antibody formation and especially in their persistence. In some of the patients, secretory antibodies were demonstrated as late as 12 months after the illness.

Adolescent↗