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Biomedical subjects

L Holt

Publications and source records attributed to L Holt.

53 records · Page 3Linked to original sources
PubMed1976

Effects of rapid increase of phenylalanine intake in older PKU children.

Twelve children formerly on strick low-phenylalanine diets were allowed to change to a moderate-protein diet over a five-week period. They were observed at home by parents, in school by teachers, and in the clinic by team members, and were evaluated periodically for phenylalanine intake, serum phenylalanine levels, activity, irritability, growth, and intelligence. Growth patterns were normal for age. Dietary phenylalanine increased sharply for all children at the end of three months, then dropped at about six months, after which it rose above the three month level. Serum phenylalanine levels followed dietary intakes, and in nine cases are staying at about 20 mg. per 100 ml. or less. The three subject above 20 mg. have serum phenylalanine of 21, 23, and 25 mg. per 100 ml. One of these has had behavioral problems and excessive weight gains in the past two years.

Adolescent↗
PubMedDate not supplied

Correlates of physical activity in chronic obstructive pulmonary disease.

BACKGROUND: Physical activity is a key dimension of functional status in people with chronic obstructive pulmonary disease (COPD), and the central target of interventions in this group. OBJECTIVES: To determine the relationships among functional performance measured as physical activity, functional capacity, symptom experiences, and health-related quality of life in people with COPD. METHOD: Cross-sectional, descriptive study. Convenience sample of 63 outpatients with COPD studied prior to entry into a pulmonary rehabilitation program. RESULTS: Daily physical activity, as measured by an accelerometer, was strongly associated with maximal distance walked during a 6-minute walk test (r = .60, p < .00), level of airway obstruction (r = .37, p < .01), walking self-efficacy (r = .27, p < .05), and physical health status (r = .40, p < .01). Physical activity was not correlated with self-report of functional status. The only predictor of physical activity was the 6-minute walk test. CONCLUSIONS: Accelerometer measurement of functional performance was most significantly related to walking abilities. This methodology represents a novel approach to measuring an important dimension of functional status not previously well quantified.

Activities of Daily Living↗
PubMedDate not supplied

The adolescent in accident & emergency.

The needs of adolescent patients attending accident and emergency departments may not be recognised by nurses due to ignorance of the nature of adolescent development, and prejudice over perceived self-injurious behaviours. The author unravels some of the mysteries behind the motivating forces of adolescent behaviours, and offers guidance to nurses who may be caring for what is understood to be a 'difficult' patient group.

Accidents↗
PubMedDate not supplied

Preventing infant deaths: a descriptive study of one high-risk neighborhood.

This study examines whether 72 infant deaths in one urban neighborhood in one year could have been prevented and if so, how. The neighborhood was targeted for a Maternal and Child Health Block Grant demonstration project because of its combination of low income and high rates of unemployment, teenage births, and infant mortality. Using a replicable set of decision rules, a committee consisting of a practicing obstetrician, a psychologist, and a social worker-epidemiologist used linked birth and death certificates to determine whether each death might have been prevented using available resources. Our criteria were designed to be somewhat conservative, in that no death was ruled preventable unless the evidence available from the birth or death certificate suggested that an available resource had clearly been called for and had not been used. Our results indicated that 25 percent of these infant deaths might have been prevented through the provision of maternal or infant transport, adequate prenatal care, immediate medical care, or alteration of the family environment. Each intervention is discussed in light of the particular circumstances of the neighborhood and current financial and political limitations.

Child Health Services↗