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Biomedical subjects

L Humair

Publications and source records attributed to L Humair.

At least 19 recordsLinked to original sources
PubMed1991

Different clinical presentations of a lupus anticoagulant in the same family.

A young man who had suffered several episodes of deep-vein thrombosis of the legs since the age of 20 had a myocardial infarction at the age of 33, at which time both a prolonged partial thromboplastin time (PTT), compatible with a lupus anticoagulant (LA), and decreased fibrinolytic capacity (FC) were found. His sister presented with deep-vein thrombosis of a leg and subsequent pulmonary embolism when she was 18 years old. She had a miscarriage three years later and developed a hemolytic-uremic syndrome at the age of 35. The PT and FC were normal. Laboratory investigations of the parents revealed positive antinuclear antibodies in the mother's serum but no anomaly in the father. This study suggests a familial tendency to develop autoimmune disorders associated with LA and thromboembolic complications related to decreased FC.

Adult↗
PubMed1989

[Tamponade and central venous catheter. Apropos of a case].

We report the case of a patient who developed cardiac tamponade after insertion of a central venous catheter. Often in such situations the first symptoms of this severe complication are late and thus delay correct diagnosis. In our patient the critical situation was recognized only after hemodynamic measurements and echocardiography. Emergency pericardiocentesis was followed by a dramatic improvement. The cardinal features of this serious event and the preventive measures to be taken to avoid this situation after placement of a central venous line are discussed.

Cardiac Tamponade↗
PubMed1988

[Myocardial infarct following cocaine abuse].

The case is reported of a young male who presented with massive anterior myocardial infarction after sniffing cocaine. The cardiovascular complications of cocaine abuse are numerous (sudden death, arrhythmia, myocardial infarction, myocarditis) and are being reported more and more frequently in the literature. Thoracic or abdominal pain in any patient known to abuse cocaine should be thoroughly investigated, despite the youth of these patients.

Adult↗
PubMed1987

[5 cases of Mediterranean boutonneuse fever in Switzerland].

The Boutonneuse Fever also called Marseilles or Eruptive Mediterranean Fever is an common disease in mediterranean area, in Africa and Indien. Rickettsia conorii is the microorganism involved and Rhipicephalus sanguineus is the most common vector. In Switzerland, this dog's tick don't exist in the nature, but it may be introduced by a dog contaminated elsewhere outside of the country and remain alive in our houses. It the reason why this disease is very uncommon in Switzerland. However, it may be observed in people coming back from vacation or in patients in contact with imported Rhipicephalus. In this paper, five cases of Boutonneuse Fever diagnosed between 1980 and 1985 are reported. The epidemiological relationships between four of these cases are of special interest. The clinical picture of the disease is presented with the different serological tests useful in confirming the diagnosis. Prevention and treatment are discussed.

Adult↗
PubMed1986

[Venous thrombosis in central venous catheterization: incidence and promoting factors].

The frequency of venous thrombosis during central vein catheterization was prospectively studied in a group of 51 patients (53 catheterizations) during a 10-month period. 12 catheterizations (23%) resulted in thrombosis as revealed by phlebography. Of these, 11 were due to catheters whose site of entry was the upper limb. No other favoring factors (osmolality of the infused fluids, length or catheterization etc.) were detected. Ideally, to avoid thrombosis, central venous catheters should be inserted via the jugular or the subclavian vein, while bearing in mind that these other routes are not devoid of complications either.

Adolescent↗
PubMed1986

Cytomegalovirus primo-infection in a patient with idiopathic proctitis.

A young heterosexual man, suffering from a low-grade, idiopathic proctitis, who developed severe rectal ulcerations at the time of a primary cytomegalovirus (CMV) infection is described. CMV was cultured from the rectum on two occasions. Sero-conversion and the appearance of a specific IgM antibody response to CMV were documented, suggesting that this was a case of a primo-infection by CMV, and not one of reactivation of latent CMV infection.

Adult↗
PubMed1985

Disseminated intravascular coagulation and acute myocardial necrosis caused by lightning.

A 24-year-old woman was struck by lightning and suffered 20% second degree burns. She was admitted after cardiac and respiratory arrest. Despite intensive supportive care she died 24 h later of cardiogenic shock complicated by disseminated intravascular coagulation. At autopsy there was myocardial necrosis. Disseminated intravascular coagulation and myocardial necrosis are only rarely described as complications of lightning.

Adult↗
PubMed1984

Vascular spasm and gangrene during heparin-dihydro-ergotamine prophylaxis.

A case is reported of a multiple trauma victim who developed severe vascular spasm whilst receiving heparin-dihydro-ergotamine thromboembolic prophylaxis which ultimately led to amputation of the right foot. Identification of high risk groups for this complication is attempted from a review of the literature. Treatment should be with intra-arterial or intravenous nitroprusside or nitrates. Little information is as yet available on the use of prostacyclin in this condition.

Adult↗
PubMed1984

Erosive group G streptococcal arthritis. Case report and review of the literature.

A case of Group G streptococcal arthritis in a previously healthy man is reported. The 2nd and 3rd metatarso-phalangeal joints of the left foot were simultaneously affected. Unusual erosive joint destruction occurred in spite of early therapy and clinical improvement. Circulating immune complexes were raised and were not completely normal at 1 year.

Aged↗
PubMed1983

[Periarteritis nodosa in a patient carrying simultaneously HBs, HBc and HBe antigens and anti-HBs antibodies].

A patient was recently observed who was a carrier simultaneously of the HBs antigen and the HBs antibody after hepatitis. He presented with a multisystem disease affecting the peripheral nervous system, the prostate and the bladder. Biopsy of these two latter organs demonstrated necrotizing vasculitis compatible with periarteritis nodosa. An atypical immunological response to the hepatitis B virus, as found in our patient, may induce extrahepatic lesions.

Aged↗