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Biomedical subjects

L I Fil'chikova

Publications and source records attributed to L I Fil'chikova.

At least 19 recordsLinked to original sources
PubMed1993

[Electrophysiological methods in assessing the risk for the development of multiple sclerosis in adolescents with monosymptomatic optic neuritis].

Pattern electroretinograms and visual evoked potentials (VEP) were investigated in response to reversal checker-board patterns with different sizes of checks in 13 adolescents with monosymptomatic optic neuritis in acute period and in the course of convalescence 1-2 and 12-36 months after the disease onset. All the children underwent computer tomography of the orbit and brain. The results allowed identification of high and low multiple sclerosis risk groups. The high risk can be proved by a progressive increase of VEP latency 1-2 months after the disease onset and its significant advance in later period of optic neuritis. Normal VEP latency in late optic neuritis shows a low degree of its development.

Acute Disease↗
PubMed1989

[The prognosis of the visual results of treating children with congenital cataracts based on visual evoked potentials].

Examination of visual induced potentials on reversible chess-pattern in 46 children with bilateral congenital zonular cataracts before and after surgical intervention has revealed correlation between these potentials and degree of lens opacification. After cataract extraction, positive dynamics of the potentials was observed in case of slightly opacified lenses and was absent in intensive lens opacification. The authors consider it reasonable to use visual induced potentials for prognosticating visual results after surgical treatment of bilateral congenital zonular cataracts, this being of particular importance for early surgical interventions.

Cataract↗
PubMedDate not supplied

[Human evoked potentials during perception of simple and complex visual stimuli].

Visual evoked potentials were recorded in children and juveniles with normal vision upon presentation of "blank" and checkboard patterns with different size of checkboard cells (10,20,40,60 and 120 angular minutes). A high degree of dependence was established both of early and later components on physical stimulus parameters: pattern structures (diffuse photic stimulus, checkboard pattern), the number of contrast borders (different sizes of checkboard cells). Maximal EP was recorded upon presentation of checkboard patterns with cells of 20 to 60 angular minutes. This is discussed as related to the size of receptive fields in man. Attraction and distraction of attention, while causing some amplitude changes mainly in later components (V and VII) amplitude did not considerably influence the EP configuration.

Adolescent↗
PubMedDate not supplied

[Visual evoked potentials in children with congenital glaucoma].

Phasic and established visual evoked potentials (VEP) to homogeneous light field and chess patterns were studied in 25 patients (48 eyes) aged 1.5 months to 9 years with different stages of congenital glaucoma and in 114 age-matched healthy children. Patients with almost absolute and far progressed stages of the disease presented with gross changes of VEP to both large- and small-cell chess patterns. In patients with the initial stages of decompensated congenital glaucoma VEP to mostly large-cell chess patterns were altered. These data evidence the usefulness of examining the VEP to stimuli with low spatial frequency for the early detection of congenital glaucoma.

Age Factors↗
PubMedDate not supplied

[Visual evoked potentials in chessboard pattern reversion in children with optic neuritis].

Visual evoked potentials (VEP) to chess pattern reversion were studied in 17 children with optic neurites during the acute stage and in the course of convalescence 1-2 months and 1-3 years after the disease onset. Coarse VEP changes were detected in the patients during the acute stage of optic neuritis. A positive time course of VEP was followed up in late periods after the acute attack of the disease. Despite normalization of vision acuity, no complete restoration of VEP to small-cell chess patterns was seen. The findings evidence that studies of VEP to chess pattern reversion should be carried out to detect subclinical involvement of the optic nerve and to timely diagnose optic neuritis in children.

Acute Disease↗
PubMedDate not supplied

[Examination of the optic nerve state in children with orbital injuries].

The results of comprehensive examinations of 13 children with orbital injuries, in whom injuries to the optic nerve were diagnosed, are analyzed. Computer-aided tomography and examinations with visual evoked potentials helped detect the signs of optic nerve injuries in the first days after the injury even in cases without ophthalmoscopic changes. Grave disorders of the involved eye visual evoked potentials were detected, that evidenced organic changes of the third neurone, despite high vision acuity. Disordered visual evoked potentials of the intact eye as against age-specific norm were detected in 8 children.

Adolescent↗
PubMedDate not supplied

[An objective method of examining visual acuity in children with amblyopia].

The authors analyze the results of vision acuity estimation with the use of visual evoked potentials (VEP) and Ye. M. Orlova's table in infants with amblyopia due to strabismus or impaired refraction. The results of electrophysiologic and clinical examinations correlated in 80 percent of cases, this proving the desirability of the VEP method for assessment of the vision acuity in infants.

Amblyopia↗
PubMedDate not supplied

[Visual evoked potentials to structured stimuli in children with cataracts].

EPs elicited by diffuse light flashes and check patterns, were studied in children and juveniles with congenital and traumatic cataract, during different periods and various durations of deprivation, as well as in a control group of children and juveniles with normal vision. Specific age characteristics were found in the EPs to check patterns in seven years-old children. In children with congenital cataracts significant changes in the shape and amplitude-temporal EP parameters were recorded. In children with traumatic cataracts, presumably developed after the end of the sensitive period, the changes in EPs were much less pronounced. The obtained data are discussed from the point of view of the duration of the sensitive period of the formation of the visual function in humans and of informative value of different EP components.

Adolescent↗
PubMedDate not supplied

[Effect of the spatial frequency of sinusoidal gratings on amplitude and temporal parameters of visual evoked potentials in man].

Visual evoked potentials (EPs) in response to sinusoidal gratings of different contrast, with spatial frequencies of 0,5-15 cycles/grad presented in "on-off" order, were studied in six grown-up subjects with normal sight. Peak latencies of all EP components and the amplitude of the relatively early N95-130-P-120-190 complex increased with increasing spatial frequency. Presentation of low-frequency gratings led to an increase of the late EP complex (N150-230-P 210-290). The EP configuration in response to sinusoidal gratings of different spatial frequencies determined by the dominance of the early or late EP complex is supposed to reflect involvement of independent mechanisms of processing of information on low or high spatial frequency differently localized in the visual cortex.

Adult↗
PubMedDate not supplied

[Visual evoked potentials in the evaluation of visual acuity in infants].

Vision acuity was assessed by visual evoked potentials (VEP) in response to low-frequency chess pattern reversion in 31 full-term healthy babies aged 6 to 28 weeks. The mean vision acuity of babies aged 6 to 9 weeks was 0.5 +/- 0.01, of those aged 16 to 18 weeks 0.1 +/- 0.01; in babies aged 24 to 26 weeks vision acuity was at least 0.14, but still lower than in normal-sighted adults. The authors emphasize the advantages of low-frequency chess pattern reversion in assessment of vision acuity from VEP in babies.

Adult↗