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Biomedical subjects

L I Guseva

Publications and source records attributed to L I Guseva.

15 recordsLinked to original sources

[The hemostatic homeostasis of patients with malignant neoplasms of the larynx, stomach and uterine cervix during radiotherapy and radiosensitization with metronidazole].

In 90 patients with malignant neoplasia of larynx, stomach and cervix uteri the functional state of hemostasis was investigated within the process of radiotherapy and in radiotherapy and radiosensitization by metronidazole. Aim of this work is to answer the question if metronidazole affects the state of organism besides its effect on radiosensitivity of tumor tissue, especially the system of hemostasis, the impairment of which can not seldom result in thrombohemorrhagic complications in oncologic patients as is known. It was pointed out that the thrombophilic status of the blood of patients with stomach carcinoma continues to be unchanged and the patients are endangered for thrombosis potentially. In consequences of radiotherapy and doses of metronidazole the capacity for adhesion is decreased in thrombocytes of patients with laryngeal and cervical carcinomas to a high degree, whereby the thrombogenic potential of blood is reduced and with that the risk for origin of intravascular thrombosis.

Combined Modality Therapy

[Ultrasonic examination in secondary lymphedema of the lower extremities].

The article deals with the results of ultrasonic examination (USE) of 39 patients with secondary edema of the lower extremities. The authors developed a USE method which yields objective data characterizing changes of the structure, thickness, boundaries, and firmness of the soft tissues in lymphedema of the lower extremities of various severity. It was established that lymphostasis produced a characteristic ultrasonic pattern, which, as claimed by the author, may be used in differential diagnosis of lymphatic and venous edema of the extremities.

Adult

[Acupuncture in edema of the extremities following radiation or combination therapy of cancer of the breast and uterus].

Acupuncture was carried out in 141 sufferers from late-onset radiation injuries to skin and soft tissues. 122 patients (86%) revealed clinical manifestations of edema of varying gravity in arms and legs, while 19 (14%) suffered radiation-induced neuritis or plexitis unaccompanied by edema. Radionuclide and rheographic studies as well as evaluation of hemostatic function showed acupuncture to be an effective treatment for edema and pain. It also improved lymph flow, rheovasographic indexes and normalized hemostasis. The best results were obtained in cases of stage I-II edema.

Acupuncture Therapy

[Effectiveness of various therapeutic schemes for patients with radiation edema of the extremities].

The efficacy of various therapeutic schemes: medicinal (basic therapy--BT), acupuncture (AP) and laser therapy (LT) against a background of basic therapy--was assessed and compared in 36 patients with radiation limb edema. It was established that a degree of a decrease in edemas, the improvement of indices of rheovasography grew in the following order: BT----AP----LT. The recovery of the lymph flow and immunological indices were the same in all therapeutic schemes.

Acupuncture Therapy

[Use of nicotinic acid and midocalm for correcting blood coagulation in patients with radiation edema of the extremities].

A study was made of the functional activity of platelets, plasmatic coagulation and fibrinolysis in patients with late radiation disorders of the blood and lymph flow during treatment with vasodilative drugs: nicotinic acid and midocalm. These drugs tend to decrease the functional activity of platelets and to raise the blood fibrinolytic activity. Their use is indicated to this group of patients to better their intravascular status.

Adult