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L I Iosava

Publications and source records attributed to L I Iosava.

10 recordsLinked to original sources

[Effect of thrombolytic therapy with intravenous streptokinase on the size of myocardial infarction estimated by the ECG QRS score system].

The impact of short-term intravenous large dose streptokinase injection on the myocardial infarction size estimated by a QRS score system was studied in 57 patients with primary myocardial infarction admitted to hospital at least 6 hours following the onset of the disease. There was a lower myocardial infarction size despite its localization and the time of treatment initiation when thrombolysis was successful, as evidenced by non-invasive criteria. The reliability of the QRS score system used to estimate the myocardial infarction size increased when the patients with anterior or inferior myocardial infarction and those with successful and unsuccessful systemic streptokinase thrombolysis.

Aged↗

[The action of streptodecase on the size of the focal lesion, the hemostatic system, blood rheology and microcirculation in relation to the time of the start of the treatment of patients with an acute myocardial infarct].

Fifty patients with myocardial infarction (MI) were given streptodecase intravenously (the main group). Depending on the time elapsed from the appearance of the disease symptoms and the onset of streptodecase injection, the main group was distributed into 2 subgroups (less than or equal to 4 h and 4 to 8 h). The size of myocardial injury was judged from the activity CPK and ECG mapping in 35 thoracic leads. The Size of MI in the main group was significantly less than in the control group. At the same time the 2 subgroups of the patients demonstrated no significant difference in myocardial injury. This is accounted for by the fact that the majority of the patients (75%) were given the thrombolytic between the 120th and 360th minute since the disease onset. In view of the fact that streptodecase was discovered to exert a lasting beneficial effect (10 to 14 days) on hemostasis, hemorheology and microcirculation, it is suggested that the drug be used at later times of MI to prevent and treat complications consequent on microcirculatory disorders.

Adult↗

[Relation between left-ventricular insufficiency and necrotic mass in myocardial infarction, determined by analysis of the QRS complex].

A noninvasive method, based on the analysis of QRS parameters from 10 of 12 standard ECG leads, was used to assess the size of necrosis in patients with acute myocardial infarction. A close correlation between anterior left-ventricular myocardial infarction weight and congestive left-ventricular insufficiency has been demonstrated. No such correlation was demonstrated for inferior myocardial infarction.

Adult↗