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Biomedical subjects

L I Tkachenko

Publications and source records attributed to L I Tkachenko.

At least 19 recordsLinked to original sources
PubMed1994

[Hypophyseal gonadotropic function in gout].

Gonadotropic function of hypophysis was studied in 109 patients with gout. Raised level of luteinizing hormone (LH) was found in men while women had decreased content of LH and follicle-stimulating hormone (FSH). Severe lesions of joins and kidneys were associated with suppressed FSH secretion. The authors consider correction of hormonal dysfunction in gout to be advisable. Certain correlative relations were established to exist between levels of gonadotropins, sex hormones and indices of purine metabolism.

Adult↗
PubMed1993

[The clinico-pathogenetic aspects of sex dimorphism in gout].

The examination of 241 gout patients (207 males and 34 females) revealed a marked sexual dimorphism of the disease related to the articular and renal syndromes. Male gout is characterized by higher blood levels of uric acid and oxypurinole in reduced clearance of the latter, while in female gout there were hyperxanthinoxidasemia and hypo-cAMPemia. Unbalance of sex and gonadotropic hormones, which appeared multidirectional and dependent on the sex, was observed in males in the form of lower concentrations of blood testosterone and estradiol against elevated levels of progesterone and lutropin, in females manifested with hypoprogesteronemia and reduced gonadotropin.

Arthritis, Gouty↗
PubMed1987

[Analysis of early and late complications of the Duhamel and Soave operations in the treatment of developmental defects of the large intestine in children].

Under study were results of the surgical treatment of 306 patients with various defects of the colon (Hirschsprung's disease, dolichosigmoid, dolichocolon, primary megarectum). In 158 of the patients the Duhamel operation was used, 148 patients were operated on after Soave. Early postoperative complications were established in 13 patients (4.2%), late complications were found in 15 patients (4.9%). The character of the early and late complications was dependent on the kind and technique of the operation.

Adolescent↗
PubMed1987

[Clinical picture and treatment of concealed penis in children].

A method of surgical treatment of 47 patients with microphallus is described. There are two kinds of the surgical treatment of microphallus depending on its form. A new operative method is proposed for a dystopic form. Good long-term results were obtained.

Adolescent↗
PubMed1980

[Polyps of the large intestine in children].

Polyps in the large intestine is a frequent disease in children. It is more often observed in boys than in girls aged 4 to 9. In most cases solitary polyps are observed (in 73,35%). Two-three polyps are met in 21,62% of cases. Polyposis is a rare disease--0,91%. The main symptom of polyps in children is hemorrhage from the anal orifice. The method of treatment is dependent on the amount, size, height of the situs and spread of the polyps. Dissection of polyps through the rectal speculum is used more frequently, rectoromanoscope is used in rarer cases (electroexcision and coagulation). Resection of the large intestine or colotomy and ablation of polyps can be successfully used in polyposis and high situs of polyps.

Adolescent↗
PubMed1976

[Malignant kidney tumors in children].

The authors have examined 92 children with renal tumors. The treatment for Wilms tumor should be combined: preoperative irradiation, nephrectomy, postoperative irradiation. Late results were studied in 48 patients. 16 patients (33.3%) are living without the recurrence and metastases for over two years, including 4 over 5 years.

Child, Preschool↗