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Biomedical subjects

L Ireland

Publications and source records attributed to L Ireland.

13 recordsLinked to original sources
PubMed1997

Fit for whose purpose? The contextual forces underpinning the provision of nurse education in the UK.

This paper explores the implications of the contextual forces currently underpinning nurse education. It challenges the notion of a model of education which is principally founded on the concept of 'fitness for purpose'. Open acknowledgement is made that the driving forces impacting on the purchasers and providers of nurse education are different, and may be in conflict. The central tenet of this debate is based upon a growing awareness that the notion of practitioners being fit for purpose is increasingly being dictated and articulated by local purchasers. Their views may reflect financial expedience and short-term goals, arguably to the detriment of a longer term vision. Tensions also exist between purchasers' locally driven agendas and the reality that practitioners receive a nationally and internationally recognized qualification. The importance of manpower planning is also central to the debate. Solutions are offered which consider guidelines offered by a range of recent policy documents. Their contribution to the debate is assessed. Recommendations are made which recognize the need to equip practitioners with skills that have currency at point of registration, but argue that dominance must be given to the longer term goals of the educational enterprise.

Curriculum↗
PubMed1994

Behavioral phenotype in children with Turner syndrome.

Compared Child Behavior Checklist results in 103 girls with Turner syndrome (TS) ages 7 to 13 years and 52 age-matched normal girls. Subjects with TS were part of a national study in Canada to evaluate growth hormone therapy in TS. Present data were obtained at baseline. Girls with TS scored below the comparison group in Total Social Competence (p < .0001), and above it in Total Behavior Problems (p < .05), Social (p < .0001), and Attention Problems (p < .001) scales. Item analysis revealed that subjects with TS were more immature, hyperactive, and nervous, and had poorer peer relations, greater difficulty at schooling, and more problems concentrating. In children with TS, height was correlated with social competence while karyotypes involving structural abnormalities of the X chromosome were associated with more behavior problems than a missing X or mosaicism.

Adolescent↗
PubMed1991

Proteins and antigens of Pasteurella multocida serotype 1 from fowl cholera.

The protein profiles of Pasteurella multocida serotype 1 isolates and the response of chickens to serotype 1 antigens were investigated using SDS-PAGE. Patterns obtained with Coomassie blue staining of soluble protein extracts were similar. The major difference between isolates was the position of one of the major proteins in the 34-38 kDa region. When chickens were experimentally infected with a clinical isolate of P. multocida serotype 1 various proteins were recognised by immunoblotting, including one with a relative molecular weight of 34 kDa; however, no reactions were observed in the region where LPS is known to migrate. When these infection sera were used in an EIA with purified LPS obtained from Heddleston serotype 1 type strain (X-73) they reacted strongly. Serum used for serotyping isolates in the gel diffusion precipitin test recognised many antigens in common with sera from infected birds, but some antigens were specific to typing sera.

Animals↗
PubMed1984

Development of the normal gastrointestinal microflora of specific pathogen-free chickens.

The development of the normal intestinal microflora of the small intestine, caecum and large intestine of specific pathogen-free (SPF) chickens, was studied in the period from hatching to 84 days of age. No bacteria were detected in any of the sites at hatchery (day 1), but by day 3 significant levels of faecal streptococci and coliforms were isolated from all sites. The flora of the small intestine was limited to faecal streptococci and coliforms for the first 40 days and then lactobacilli became established and dominated the flora. A large variety of facultative and strictly anaerobic organisms colonized the caecum. Many of these species were transient and were only present for a limited period; after 40 days the flora stabilized to consist predominantly of faecal streptococci, Escherichia coli, Bacteroides spp. and Lactobacillus sp. The flora of the large intestine was composed of organisms also present in the small intestine or the caecum. These findings differ from previously published studies on conventionally reared chickens in that the number of species isolated and the population levels of organisms are much lower. This probably reflects the absence of continuous environmental challenge to the chickens because of the housing and feeding facilities in which the chickens were maintained.

Animals↗
PubMed1983

Clostridium fallax as a cause of gas-oedema disease in a horse.

We record a fatal case of gas-oedema disease (malignant oedema) in a 5-year-old horse. The nature of the lesion is consistent with a gas-oedema type infection due to a Clostridium spp. The causative organism was isolated and identified by conventional biochemical tests and by gas-liquid chromatographic analysis of its metabolic products as Clostridium fallax, but significant variations in the reported biochemical characteristics of Cl. fallax were detected. We believe that this is the first reported case of Cl. fallax infection in a horse.

Animals↗
PubMed1982

Small nuclear RNAs from Drosophila KC-H cells; characterization and comparison with mammalian RNAs.

Small molecular weight nuclear RNAs were extracted from cultured Drosophila KC-H cells and characterized by their electrophoretic mobilities in 5--15% gradient acrylamide gels or in 10% acrylamide-7 M urea gels. Comparison between the electrophoretic profiles of these SnRNAs with those from human and mouse cells revealed striking similarities and allowed for assignation of band nomenclatures as established for mammalian cells. Comparison of mobilities in the two gel systems also permitted correspondence between the different nomenclatures established by various groups for this class of RNAs, as well as an approximate estimate of their molecular sizes.

Animals↗
PubMedDate not supplied

Is the quest for evidence-based care detrimental to children's nursing?

Evidence-based care and the expanded role of the nurse are inexorably linked. Facets of this are found in every specialist area of nursing. Children's nurses are no exception and they have proved their commitment to family-centred care over a period of many years. However, within the ranks of nurse educationalists now employed by the universities and not the NHS new tensions have emerged. The research-led ethos of the universities demands that nurses demonstrate expertise in the field of scientific enquiry. Although the philosophy of caring and research are not incongruent, there exists the potential that family empowerment may take a back seat to academic prowess. This article examines the background to this dilemma.

Child↗