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L J DiDio

Publications and source records attributed to L J DiDio.

At least 37 records · Page 2Linked to original sources

Types of division of the left coronary artery and the ramus diagonalis of the human heart.

The surgical, clinical and radiological importance of the diagonal artery in the human heart and the extreme variability in its description prompted us to undertake its study. The investigation was performed in 150 hearts, dissected after injection of colored substance in the coronary arteries. The following results were obtained: The left coronary artery presented 3 types of division: bifurcation (54.7%), trifurcation (38.7%) and quadrifurcation (6.7%); the latter 2 patterns produced a diagonal artery. The trunk of the left coronary artery bifurcated more frequently in hearts of female Caucasians (57.1%) and male Caucasians (54.9%). It trifurcated more frequently (60%) in hearts of female non-Caucasians. The ramus diagonalis was found in 45.3% of the hearts. The incidence of a ramus diagonalis did not differ significantly between male Caucasians (45%), male non-Caucasians (42.8%) and female Caucasians (37%). However, it occurred more frequently in female non-Caucasians (66.5%). The length of the ramus diagonalis varied from 20.1 to 50 mm (79.3%) and its relative length varied from 21 to 50% of the length of the left ventricle (75.3%). The ramus diagonalis was classified as short, medium and long types, the former 2 types were most frequent.

Adult↗

Comparison of computerized tomography with magnetic resonance imaging (MRI) in the evaluation of encephalic ventricular volume.

The volume of the encephalic ventricles was determined from computerized tomographic (CT) and magnetic resonance imaging (MRI) scans of seven subjects without apparent pathology and three subjects with enlarged ventricles. Since there are many conditions in which the encephalic ventricles become enlarged such as Alzheimer's disease and hydrocephalus, accurate measurement of these structures provides (1) a valuable and safe means of aiding in the diagnosis of such conditions and (2) important follow-up information on affected patients. This paper presents the data obtained from the second phase of a three phase study. The first phase demonstrated the possibility of measuring fluid filled spaces by MRI in three phantom preparations (small, medium, and large "ventricles"). The results were compared with those obtained from the computerized tomography (CT) scans of the same preparations. This phase of the study compares the volumes obtained from CT scans with those obtained from MRI scans of the same individuals. The volumetric calculations were done with the aid of a Calcomp 9000 digital analyser programmed to compensate for the scale factor and slice thickness of the images. The results obtained from the MRI scans correlated closely with those obtained from the CT scans of the same subjects. The third and final phase of the project is the development of an MRI volumetric data base for the encephalic ventricles using a larger number of subjects.

Cerebral Ventricles↗

The papillary muscles of the left ventricle and the cardiac segments.

The relationship between the arterial anatomicosurgical segments and the papillary muscles of the left ventricle was investigated in 38 human hearts of adult individuals of both sexes. The specimens were studied after (a) vinyl acetate injection and corrosion (28 hearts) or (b) formaldehyde fixation (10 hearts). In 4 of the corrosion casts, the cardiac chambers were not filled with the plastic substance and, prior to corrosion, the position of the papillary muscles was marked with threads or pins. The anterior papillary muscle was related to the (a) anterior interventricular segment (I SV); (b) lateral (II SV); and (c) left marginal segment (III SV). The medical portion of the anterior papillary muscle is supplied by the artery of the I SV whereas the lateral portion is supplied by the artery of the II or III SV. The posterior papillary muscle was related to the (a) anterior interventricular segment (I SV); (b) left marginal (III SV); (c) posterior interventricular segment (III DV) and (d) posterior ventricular (IV SV). As a rule, the papillary muscles are supplied by more than one segmental artery, therefore, anatomical variations may play an important role in functional alterations produced by ischemic lesions of the myocardium.

Adult↗

Evaluation of encephalic ventricular volume from the magnetic resonance imaging scans of thirty-eight human subjects.

Accurate volume determination of the encephalic ventricles is of importance in several clinical conditions, including Alzheimer's presenile dementia, schizophrenia, and benign intracranial hypertension. Previous studies have investigated the accuracy with which magnetic resonance imaging (MRI) can be used in clinical practice to evaluate the encephalic ventricles. However, adequate evaluation of pathological conditions depends on a sufficient amount of morphometric data from normal subjects. To begin establishing this data base for "normal" subjects, we evaluated the MRI scans of 38 subjects found to have no apparent pathology and calculated the ventricular volume in each case by using methods previously developed in our laboratory. The results were then compared with published volumes determined from studies that used either ventricular casts or computerized tomographic scans. The average total ventricular volume for all 38 subjects was 17.4 cm3, while that for males was 16.3 cm3 and that for females was 18.0 cm3. A small but significant correlation was found between age of subject and ventricular volume, with ventricular size increasing with age.

Cerebral Ventricles↗

Volume determinations of the encephalic ventricles with CT and MRI.

The volume of the encephalic ventricles was determined from magnetic resonance imaging (MRI) scans. Since there are many conditions in which the encephalic ventricles become enlarged such as Alzheimer's disease and hydrocephalus, accurate measurement of the ventricles provides a valuable and safe means of aiding the diagnosis of such conditions and also provides important follow-up information in affected patients. The objective was pursued in a three phase study. This paper presents the data obtained from the first phase. This first phase demonstrated the possibility of measuring fluid filled spaces by MRI in three phantom preparations (small, medium, and large "ventricles"). The results were compared with those obtained from computerized tomography (CT) scans of the same preparations. These volumetric calculations were done with the aid of a Calcomp 9,000 digital analyzer programmed to compensate for the scale factor and slice thickness of the images. The phantom study showed that the results obtained from the MRI scans were better than those obtained from the CT scans in measuring the volume of water-filled cavities (ventricles) in gelatin phantoms. The average percent difference between volumes obtained by an imaging procedure compared to the actual volume as determined by water displacement was 15.8% for CT scanning and a more impressive 8.3% for MRI.

Cerebral Ventricles↗

Variation in length and termination of the ramus circumflexus of the human left coronary artery.

The length and termination of the circumflex branch of the left coronary artery were studied in 81 hearts, after injection of the coloured substance containing a radiopaque medium. The hearts were radiographed, dissected, drawn and photographed. The short type of circumflex branch, defined as a branch that did not reach the crux cordis, was found to be much more frequent (86.4%) than the long type and terminated in the majority of the cases (76.5%) as one of the posterior branches of the left ventricle.

Arteries↗

Historical aspects of the International Federation of Associations of Anatomists.

The need for closer and personal scientific exchange among anatomists, histologists, embryologists, morphologists, anthropologists, veterinarians, dentists, biologists, and zoologists, and professionals of allied health sciences, and their interest in the uniformity of the technological language they all used in teaching and research, led a group of leaders in the field of Anatomy to found the International Federation of Associations of Anatomists (IFAA).

Anatomy↗

Myocardial bridge over the right coronary artery in man.

A rare case of myocardial bridge over the trunk of the right coronary a. is described in the heart of a male, adult, Caucasian, Brazilian, whose death occurred after an automobile accident. After a review of the literature, the unusual finding is described and illustrated. Other bridges on the beginning of the right marginal a.; the right anterior ventricular a.; and on the anterior interventricular a. (left anterior descending) a. were observed. The location and significance of myocardial bridges over coronary a. are discussed.

Adult↗

Variation in length and termination of the right coronary artery in man.

The length and termination of the right coronary artery of the human heart were studied in 81 hearts, after injection of a colored substance containing a radiopaque medium. The hearts were radiographed, dissected, drawn and photographed. The long type of right coronary artery, defined as a branch that reached or ran distal to the crux cordis, was found to be much more frequent (88.8%) than the short type and terminated in the majority of the cases (71.6%) as one of the posterior branches of the left ventricle. The relationship between these findings and the so-called "coronary circulation dominance" is discussed.

Coronary Vessels↗

Anatomicosurgical segments of the human pancreas.

Two anatomicosurgical segments of the human pancreas were recognized in 30 corrosion casts after injection of the pancreatic arteries thus confirming prior anatomico-surgical studies. The right (cephalocervical) and the left (corporocaudate) segments of the pancreas are separated by a paucivascular area. They are linked by the pancreatic duct and often by a single, small artery, which may be a branch of the gastroduodenal, gastroepiploic (gastromental), or dorsal pancreatic artery. Both segments are suitable for segmental pancreas transplantation.

Aged↗

The cardiac apex and its superficial blood supply.

The cardiac apex was defined and 3 types were presented: the anatomical apex, the base of which was established at the incisura apicis cordis; the amplified anatomical apex, twice the volume of the preceding; and the geometric apex, the distal third of the ventricles. These types of cardiac apex were studied in connection with the superficial branches of the coronary arteries at their level. The investigation was conducted on 81 normal hearts (56 males and 25 females) of 60 Caucasian and 21 non-Caucasian individuals. The arteries were injected with colored gelatine mixed with a radiopaque substance. The number of branches decreased from the geometric (the largest type) to the anatomical apex (the smallest): 27 on the surface of the geometric apex, 14 on the surface of the amplified anatomical apex, and 7 on the surface of the anatomical apex. The sternocostal aspect had a higher number of superficial branches than the diaphragmatic aspect in all types of cardiac apex. Sexual differences were found in the incidence of the r posterior ventriculi sinistri intermedius on the amplified anatomical apex as it was more frequent in females than in males. In the geometric apex there were 3 branches also more frequent in females: r anterior ventriculi sinistri inferior, r posterior ventriculi sinistri lateralis I, and r posterior ventriculi sinistri lateralis IV.

Adolescent↗

Histochemical localization of prostaglandin-synthetase in the salivary glands of Praomys (Mastomys) natalensis.

The cellular distribution of prostaglandin-synthetase was studied in the salivary glands of Praomys (Mastomys) natalensis. Only the epithelial cells of the ducts showed discrete prostaglandin-synthetase activity, whereas the acini and the stroma gave completely negative results in all three salivary glands of both sexes. The presence of exogenous substrates was not required for the reaction, since identical results are observed following incubation with and without arachidonic acid. The localization of prostaglandin synthetase in the ductal epithelia of Praomys salivary glands is related to a possible regulatory role of the prostaglandins on the reabsorptive activity of the ductal cells.

Animals↗

Cytochemical demonstration of enzymatic activities of the parotid, submandibular, and sublingual glands of Praomys (Mastomys) Natalensis.

Histochemical techniques were applied to salivary glands removed from adult multimmate rodents (Praomys) of either sex to detect and localize the following enzymatic activities: acid and alkaline phosphatase, arylsulphatase, ali-esterases, beta-glucuronidase, N-acetyl-betaglucosaminidase, and L-leucyl-aminopeptidase. No reaction was observed for alkaline phosphatase and glucuronidase. The glands reacted differently to the other enzymatic activities. Alkaline phosphatase and glucosaminidase were present only in one glandular type whereas arysulphatase and esterases were present in all types although demonstrating a variable staining intensity in different glands. Sharp differences in some enzymatic activities of the submandibular and parotid glands were related to the sex of the animal.

Acid Phosphatase↗

Subcellular organization of the yolk syncytial-endoderm complex in the preimplantation yolk sac of the shark, Rhizoprionodon terraenovae.

The structure of the yolk syncytial-endoderm complex of the preimplantation yolk sac of the shark is examined by light- and transmission electron microscopy. The yolk syncytium is bounded by a membrane that is anchored to the plasmalemma of adjacent endoderm cells by desmosomes. Enlarged nuclei, rough endoplasmic reticulum, Golgi complexes, mitochondria, and other cellular organelles populate the syncytium. Microtubules and filamentous elements are also observed free in the syncytium. Yolk is present as pleomorphic droplets, the profiles of which are generally spherical but may be vesicular, especially at the periphery of large yolk droplets. Occasionally, large yolk droplets have a paracrystalline configuration. Small yolk droplets are modulated through the Golgi complex of the yolk syncytium, and it is suggested that acid hydrolases are added there. Small yolk droplets released from the maturing face of the Golgi complex are sequestered in membrane-limited packets. The membrane of the packets fuses with the membrane enveloping the yolk syncytium and the yolk droplets are released into the yolk syncytial-endoderm interspace. Subsequently, the yolk droplets are endocytosed by the endoderm. Yolk droplets disperse and fuse to form the large irregular yolk inclusions of the endoderm. Yolk metabolites are transported out of the endoderm through the yolk sac endothelium. The yolk sac endoderm thus mediates the transfer of metabolites from the yolk mass to the extraembryonic circulation.

Animals↗

Incidence and clinical significance of bridges of myocardium over the coronary arteries and their branches.

The incidence of bridges of myocardium seen on the external surface of the heart, through the epicardium, over portions of coronary arteries and their branches, was studied in 50 cadavers and found to be 78%. The bridges of the myocardium varied in size and in number (from one to six). Their location was predominantly found at the level of the anterior ventricular branch of the left coronary artery also called left anterior descending artery (52%), whereas in the territory of the right coronary artery the highest percentage was at the level of the anterior ventricular branch (12%). This myocardio-arterial relationship might be responsible for periodic or permanent reduction of the lumen, partial or total arterial obliteration, ischemia, atherosclerosis, angina, and sudden death.

Cadaver↗

Morphology of the middle rectal arteries. A study of 30 cadaveric dissections.

The middle rectal arteries were studied in 30 cadavers of adult and older individuals (29 Caucasians and one Negro) of both sexes (15 males and 15 females). The middle rectal artery was present in 56.7% of the cases, bilaterally (36.7%) or unilaterally (20%), originating from the internal pudendal (40%), inferior gluteal (26.7%), internal iliac (16.8%), and less frequently from other pelvic branches. The average external diameter of the middle rectal artery was found to be 1.7 mm, its average length about 7 cm, and the point of penetration in the rectal wall about 6 cm (average) superior to the anus. The most frequent sites of the rectal wall pierced by the middle rectal arteries were the anterior (50% of the cases) and posterior (45%) quadrants of the rectum, whether isolated or combined (43.3%). These anatomical features justify, when needed and possible, the preservation of the middle rectal artery in surgical interventions on related organs. The term middle rectal arteries in Nomina Anatomica should be changed to inferior rectal arteries and indented under internal pudendal artery; the current term inferior rectal arteries should be changed to anal arteries to follow the already adopted division of the terminal intestine into rectum and anal canal.

Aged↗