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Biomedical subjects

L J Dusci

Publications and source records attributed to L J Dusci.

At least 55 records · Page 3Linked to original sources
PubMed1978

Gas-liquid chromatographic determination of ibuprofen in human plasma.

A gas-liquid chromatographic method for the estimation of Ibuprofen in human plasma is described. The procedure is rapid with the free drug being analysed thus eliminating the need for any derivatisation steps. The method allows the drug concentrations to be analysed down to a level of 2 mg/l using 2 ml plasma.

Chromatography, Gas↗
PubMed1977

Determination of paracetamol in human serum.

A procedure is described that gives quantitative extraction of paracetamol from serum. This, together with derivatisation and gas chromatography, provides a simple method that facilitates the rapid estimation of the drug in serum in the range 5--500 mg/litre.

Acetaminophen↗
PubMed1977

Rapid identification of drugs in the overdosed patient.

A rapid analytical procedure is described for a variety of drugs that could be present in the overdosed patient. The technique used gives quantitative results for most of the drugs analyzed in serum using gas chromatography and incorporates thin-layer chromatography and spot tests for drug confirmation. The procedure is novel for it relies on the initial extraction of acidics, basics, and neutrals from serum acidified with hydroxhloric acid.

Chromatography, Gas↗
PubMed1977

Direct extraction procedure for the analysis of neutral drugs in tissue.

This paper describes an efficient extraction technique for the determination of neutral drugs in tissue. The extracts are clean and can be analyzed by gas liquid chromatography. The method gives good recoveries of most of the neutral drugs and the sensitivity is such that therapeutic levels can easily be detected.

Humans↗
PubMed1976

Rapid digestion and flameless atomic absorption spectroscopy of mercury in fish.

A rapid method is described for the determination of total mercury in fish samples. The sample is digested with nitric acid-sulfuric acid-potassium permanganate, and then reduced and aerated for measurement by flameless atomic absorption spectrophotometry. The average recoveries of organic and inorganic mercury added to fish were 93 and 95%, respectively. The uniformity of mercury levels in shark tissue has also been investigated.

Animals↗