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Biomedical subjects

L J Girard

Publications and source records attributed to L J Girard.

At least 19 recordsLinked to original sources

Use of grafts smaller than the opening for keratoconic myopia and astigmatism. A prospective study.

A prospective study was conducted on 15 consecutive keratoconic eyes to evaluate the use of grafts smaller than the opening in keratoconic myopia and astigmatism. All surgeries were performed by the senior author. Average age of the patients was 41.1 years. Average follow-up was 1.6 years. After all sutures were removed, results showed an average decrease in myopia of 13.24 diopters (D) (range 1.75 to 23.25) principally from corneal flattening and a small reduction in axial length. Average postoperative spherical equivalent was -2.17 D (range +1.50 to -7.25). The average postoperative astigmatism was 3.78 D (range 1.75 to 6.00). This study and a previous retrospective study suggest that the use of grafts 0.25 mm smaller than the opening, i.e., 7.50/7.75 mm, for penetrating keratoplasty in keratoconus is justified.

Adult

Subluxated (ectopic) lenses in adults. Long-term results of pars plana lensectomy-vitrectomy by ultrasonic fragmentation with and without a phacoprosthesis.

The long-term results of pars plana lensectomy-vitrectomy by ultrasonic fragmentation for 18 consecutive subluxated (ectopic) lenses were retrospectively reviewed. There were no serious operative or postoperative complications at the 16-year follow-up. Visual acuity of 20/15 to 20/50 was obtained in 16 (89%) of 18 eyes. Lensectomy-vitrectomy for subluxated lenses appears to be a relatively safe and effective procedure. The technique can be combined with a phacoprosthesis (intraocular lens implant) in adults.

Adult

Evisceration implant of Proplast II. A preliminary report.

An evisceration implant made from a highly porous inert, Teflon fluorocarbon, Proplast II, and the surgical technique of implantation is described. The implant was used in four eyes without complications. The implant and technique have many advantages: the ability to absorb antibiotics: the ability to prevent extrusion and infection; the fact that it is lightweight, black in color, and capable of preserving the cornea.

Aluminum Oxide

Ligneous conjunctivitis after pingueculae removal in an adult.

A 45-year-old man who had uneventful excision of bilateral pingueculae developed bilateral membranous lesions involving the bulbar conjunctivae and corneas. Histologically, the membranes were composed mainly of large fibrinous deposits intermixed with acute and chronic inflammatory cells with areas of fibroblastic and capillary proliferation resembling granulation tissue. By electronmicroscopy the amorphous acidophilic masses were composed of electron-dense, fibrillar material with a periodicity of 10-12 mm, which was consistent with fibrin. Despite mechanical removal of the membranes, they continued to recur rapidly over a period of several months. The lesions apparently responded slowly to topical enzymatic therapy that consisted of hyaluronidase (175 U/ml) and alpha-chymotrypsin (1:5000) drops. Follow-up examination, approximately 1 year after surgery, revealed that the patient was asymptomatic. Ocular examination disclosed slight persistence of gelatinous membranes on the bulbar conjunctivae, most prominent in the left eye.

Adipose Tissue

'Avitria'.

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Humans

Effect of penetrating keratoplasty using grafts of various sizes on keratoconic myopia and astigmatism.

The records of 72 consecutive keratoconic eyes undergoing penetrating keratoplasty were reviewed for changes in myopia and astigmatism. Ages of the patients averaged 32.7 years. All sutures were removed after three months. Follow-up average was 40.2 months. Results showed an average decrease in myopia of 6.63 diopters (D) in 60 eyes (82.86%) and an average increase in myopia of 1.88 D in 12 of 70 eyes (17.14%). The decrease/increase in myopia and postoperative astigmatism was compared for grafts equal to the opening, grafts smaller than the opening, and grafts larger than the opening. The largest average decrease in myopia was 13.86 D (range 6.63 to 20.00), which occurred when a graft smaller than the opening was used (P less than .01). This group also showed the least postoperative astigmatism (2.82 D) (P less than or equal to .01). From this study, it appears that the use of a graft 0.25 mm smaller than the trephine opening in the host (i.e., 7.50 mm graft/7.75 mm opening) for penetrating keratoplasty in keratoconus is justified. A prospective study is now in progress.

Adolescent