PubMed Health⌕ Search

Biomedical subjects

L J Henderson

Publications and source records attributed to L J Henderson.

At least 19 recordsLinked to original sources
PubMed2000

Diagnosis, treatment, and lifestyle changes of interstitial cystitis.

Interstitial cystitis (IC) is a chronic inflammation of all the layers of the bladder wall. As it is difficult to diagnose and it affects mostly women, many physicians misdiagnose it as a psychological problem. Almost half a million individuals in the United States suffer from this cureless disorder. This article will review the anatomy, physiology, etiology, diagnosis, treatments, and current research foci of IC, along with the effects of the disease on lifestyle and personal issues from the patient's perspective.

Adult↗
PubMed1996

Testing prototype products in the operating room.

Historically, the discussion of which products to use in a hospital has centered around disposable versus reusable products; however, new technology has produced a line of products that are not only disposable but degradable. Perioperative staff members at Redmond Regional Medical Center, Rome, Ga, participated in the testing, evaluation, and use of these prototype products during their development.

Disposable Equipment↗
PubMed1996

The glass ionomer-dentine bond. A comparison of destructive and non-destructive assessment.

The traditional laboratory testing (mechanical testing and microleakage testing) of the adhesion of restorative materials to dentine is of a destructive nature. A non-destructive laboratory method of testing the material-dentine bond using ultrasonics has been devised and compared to mechanical shear testing. Similar results were obtained with both testing methods. It this study thermocycling was shown to have no statistically significant effect on the glass-ionomer dentine bond.

Composite Resins↗
PubMed1995

Angioplasty with stent placement in peripheral arterial occlusive disease.

Percutaneous transluminal balloon angioplasty (PTBA) is a minimally invasive and effective adjunct treatment for patients with atherosclerotic peripheral vascular disease. This surgical technique involves placing an intraarterial balloon within an obstructing arterial lesion and forcibly dilating the balloon under fluoroscopy. The PTBA technique has become an accepted interventional therapy for iliac artery stenoses. In selected patients with stenotic lesions of the iliac artery, percutaneous transluminal angioplasty (PTA) with the use of an intravascular stent may be an alternative to traditional aortofemoral bypass surgery. The PTA procedure involves only a needle entry site in one or both groins as opposed to an incision exposing the entire abdomen. The hospital stay for the average patient undergoing PTA of the iliac artery is three days as opposed to seven days for the patient undergoing aortofemoral bypass, and the patient may return to normal activity in a much shorter period of time after a PTA procedure.

Angioplasty, Balloon↗
PubMed1993

The surface finish of light-cured composite resin materials.

A necessity for any dental restorative material is its ability to take and maintain a smooth surface finish. Composite resin restorative materials with fillers and matrix of differing hardness are difficult to finish and polish. The use of aluminum trioxide discs is a popular and acceptable method of finishing composite restorative materials where the material is accessible. Burs and stones are used for finishing and polishing inaccessible areas. This study was undertaken to compare the surface finish of composite resin restorative material when finished with white stones, superfine diamond burs and aluminum trioxide discs. The finished surface was measured with a profilometer and the roughness average value used to compare the surfaces. The aluminum trioxide discs gave the best and most consistent results. It was possible to attain similar results with the superfine diamond bur. However, the results were highly variable. None of the methods used achieved the smoothness of composite resin cured against a transparent matrix.

Aluminum Oxide↗
PubMed1992

Dentin adhesives and microleakage in cervical resin composites.

This paper reports the effect of dentin bonding agents on marginal leakage in cervical cavities without the classical cavity preparation design. Wedge-shaped cervical cavities were cut on extracted teeth with the gingival cavosurface margin of each cavity involving dentin. The specimens were randomly assigned to three groups of 40 each: Group 1 (control), restored with Fuji glass ionomer; Group 2, restored with Scotchbond 2 adhesive and Silux Plus resin and Group 3, restored with Tenure adhesive and Perfection resin. Half of the specimens in each group were thermocycled. All specimens were then stored in basic fuchsin dye after which microleakage of the restorations was assessed by dye penetration. A grading scale of 0 to 3 was used as the scoring criteria. The results showed that differences were more pronounced at the gingival margin. The control group specimens exhibited the least microleakage. There was no significant difference between thermocycled and non-thermocycled specimens for each category of materials used. There was, however, a significant difference between the experimental groups and the control groups. The dentin adhesives tested did not completely eliminate microleakage at the gingival margin of cervical cavities.

Analysis of Variance↗
PubMed1990

Effect of thermal stress on dentin adhesives used individually and in combination.

Polymerization shrinkage remains an inherent problem in composite restorations. Dentin adhesives generally improve bonding to dentin but do not consistently provide leak-free restorations. This study evaluated a dentin adhesive that bonds to dentinal calcium and another that bonds to dentinal collagen when used separately and in combination. The measurement of contraction gaps at the restoration-dentin interface was used as the means of testing the effectiveness of dentin adhesion. The effect of thermal stress on the dentin-polymer bond was also investigated. Results showed that the bisphenyl A glycidyl methacrylate (BISGMA)-based dentin adhesive was more effective when compared with the hydroxyethyl methacrylate (HEMA)-based adhesive. When used in combination, the mean contraction gaps of cavities were not found to be significantly better than those treated with only the BISGMA-based adhesive. Thermal stress reduced the effectiveness of dentin adhesives whether applied individually or in combination.

Composite Resins↗
PubMed1989

Gluma dentin adhesive: effectiveness and shelf life.

The purpose of this study was to test the effectiveness and shelf life of a commercially available glutaraldehyde/methacrylate dentin adhesive (Gluma). The measurement of marginal contraction gaps in 320 cavities restored over a period of 415 days was the basis for these determinations. The results showed that Gluma dentin adhesive was more effective with one of the two composite restorative materials used for the study, and that the shelf life of Gluma exceeded 415 days.

Aldehydes↗
PubMed1989

The effect on marginal leakage when using two dentine adhesives in combination.

This study was undertaken to test the effectiveness of using two dentine adhesives in combination. One of the dentine adhesives used adhered to the calcium in the dentine while the other dentine adhesive adhered to the organic portion of the dentine. It was hoped by using them in combination that their actions would complement each other producing composite restorations with gap free margins. Results showed an increase in the number of gap free restorations but the marginal contraction gaps were not entirely eliminated.

Adhesives↗
PubMed1989

The development of a composite restorative system.

Composite resin restorative materials have been used in dental practice for over 25 years. The original composite resins were subjected to discolouration and marginal breakdown. These problems have largely been overcome with the exception of marginal gaps at the dentine-restoration interface. The introduction of dentine adhesives has reduced but not eliminate this problem. This study shows how the marginal gaps at the dentine-restoration interface were significantly reduced firstly by the introduction of an intermediate resin and then further by using a dentine adhesive.

Adhesives↗
PubMed1988

Glutaraldehyde-methacrylate dentine adhesive: the relationship between cavity site and marginal contraction gaps.

Previous studies have shown that dentine adhesives reduce or eliminate contraction gaps in composite restorations. This study examined the relationship between cavity site and contraction gaps when two dentine adhesives were used in combination with two composites. One hundred and fifty-two cavities, each measuring 2.0 mm diameter and 1.5 mm depth, were prepared on side surfaces of extracted teeth, with each surface classified into three levels: upper, middle and lower. The dentine adhesives and composites were randomly assigned to the cavities. Four pre-determined, diametrical measurements of contraction gaps were made for each restored cavity using a Nikon Measurescope. Measurements yielded overall mean contraction gaps of 0.229, 0.262, and 0.260 for upper, middle and lower levels on the crown; the differences between means were not statistically significant. Type of dentine adhesives and composites influenced the size of contraction gaps rather than cavity site.

Composite Resins↗
PubMed1985

Ascorbic acid antagonizes the behavioural effects of LSD in cats.

Pretreatment with ascorbic acid (500 mg kg-1 i.p.) antagonized the behavioural effects of lysergic acid diethylamide (LSD) and apomorphine, but not 5-methoxy-N,N-dimethyltryptamine, in cats. The data support the hypothesis that these behavioural effects in cats are due to drug action at both 5-HT and dopamine receptors, and that the action of LSD at dopamine receptors is modulated by ascorbic acid.

Animals↗
PubMed1984

Buspirone increases locus coeruleus noradrenergic neuronal activity in vitro.

Buspirone, a non-benzodiazepine anxiolytic agent, produced dose-dependent increases in the activity of norepinephrine-containing locus coeruleus neurons recorded from mouse brain slices in vitro. The response was not changed in a low calcium/high magnesium incubation medium, indicating that the observed effects were the result of a direct action of buspirone on locus coeruleus neurons. These data suggest that noradrenergic neurons may not be as important in mediating anxiety states as previously suggested.

Action Potentials↗
PubMed1983

Mescaline elicits behavioral effects in cats by an action at both serotonin and dopamine receptors.

The characteristic behavioral effects of mescaline in cats were nearly completely blocked by pretreatment with low doses of either a specific serotonin antagonist (methysergide) or a dopamine specific antagonist (haloperidol). These blocking effects were not due to non-specific actions, since methysergide did not block the behavioral effects of apomorphine, and haloperidol did not block the behavioral effects of 5-methoxy-N,N-dimethyltryptamine. Thus, it appears that the behavioral effects of mescaline are dependent upon the simultaneous action of the drug at both serotonin and dopamine receptors.

5-Methoxytryptamine↗