Biomedical subjects
Publications and source records attributed to L J Rossoff.
A patient with renal failure who received acute peritoneal dialysis rapidly developed a tension hydrothorax which required immediate drainage of the pleural space. Rapid identification and therapeutic intervention for this rare complication of peritoneal dialysis is necessary because of its life-threatening potential.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A 32-year-old man with a ten-year history of bilateral cervical adenopathy, parotid gland swelling, and a posterior mediastinal mass, presented with headaches. A CAT scan of the head revealed a suprasellar mass. Craniotomy and biopsy of this lesion led to a diagnosis of sinus histiocytosis.
In an attempt to determine whether PO2 or O2 saturation is stimulus for the hypoxic ventilatory drive, we studied 2 brothers with the high O2 affinity hemoglobin Ranier (P50 approximately equal to 12 mm Hg). The ventilatory response to PO2 was normal. The O2 saturation did decrease slightly, and the ventilatory response to the decrease in O2 saturation was greatly exaggerated. We conclude that these findings are consistent with either of 2 possibilities: (1) that PO2 provides the stimulus to the hypoxic ventilatory response, or (2) that patients with high-affinity hemoglobin have increased sensitivity to arterial O2 desaturation.
Explore the source record for details and available documents.