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Biomedical subjects

L J van Rijn

Publications and source records attributed to L J van Rijn.

5 recordsLinked to original sources
PubMed1992

Visually induced cycloversion and cyclovergence.

Binocular cyclorotatory (torsional) eye movements in response to visual patterns, which oscillated sinusoidally in the frontal plane, were recorded with scleral induction coils in human subjects. Conjugate cycloversion and disjunctive cyclovergence were directly compared by in-phase and out-of-phase oscillation of the same pattern. Stimulus motion had a frequency of 0.2 Hz and amplitudes of 2-8 deg. Both response types had a similar and low gain (about 0.2 averaged over all subjects). Cycloversion showed no time lag, while cyclovergence lagged by about 600 msec. Non-fusible patterns were effective in eliciting cycloversion, but not cyclovergence. Apart from this, the nature of the pattern (randomly distributed dots, regular rows of dots, horizontal or vertical grating, Julesz stereogram or images with a pictorial significance) had only the slightest effect on the magnitude of the responses.

Adult↗
PubMed1987

Suprofen versus paracetamol after oral surgery.

A randomized double-blind trial was performed to evaluate efficacy and tolerability of suprofen 200 mg (Suprocil) in comparison to paracetamol 500 mg after surgical extraction of a wisdom tooth. The study lasted 4 days per patient at the longest. Pain intensity and pain relief were evaluated by the patients using a visual analog scale. A total of 59 patients took part in the study; of these, 30 were on suprofen and 29 on paracetamol. The 30-min pain relief with paracetamol was superior to that obtained with suprofen. Roughly, the 90-min pain relief scores were somewhat higher for suprofen than for paracetamol. However, none of the differences were statistically significant. No significant difference was seen between the 2 treatment groups with respect to the frequency of the number of capsules taken per day. Broadly, the efficacy was good or excellent in 18 patients in each group. With suprofen, there were 8 moderate results and 4 insufficient ones. With paracetamol, 6 results were moderate and 5 insufficient or worse. No significant differences between the 2 treatments was seen. Tolerability was rated good by all but 1 patient in each treatment group; with suprofen, 1 result was moderate, while with paracetamol, 1 result was poor. Adverse reactions occurred in 3 patients on suprofen and in 2 patients on paracetamol, though these reactions could not be related to the use of the drug itself.

Acetaminophen↗
PubMed1986

Experimental gingivitis and frequency of tooth brushing in the beagle dog model. Clinical findings.

The aim of this experiment was to study clinical parameters when 3 different frequencies of tooth brushing were applied to sites of experimental gingivitis in beagle dogs. 12 beagle dogs, at the start of the experiment 2 years of age, were used. After a thorough cleaning, the maxillary left and right first, second and third premolars were brushed daily for a period of 8 weeks. Subsequently, for 4 weeks, all brushing was omitted in order to establish an experimental gingivitis. After this pre-experimental period, the dogs were distributed into 3 groups of 4 dogs each: one group was brushed 7 times a week, a second was brushed 3 times a week and the third group was brushed only once a week. Brushing was carried out for 24 weeks, only on the right sides of the upper jaws, the left upper jaws serving as controls. At regular intervals, plaque index, gingival index and probing depths were assessed. A brushing effect was calculated for each dog, to include information on all within-dog and between-dog variations. The present study demonstrated that only by brushing every day can clinically healthy gingivae be obtained in the beagle dog model with experimental gingivitis at baseline. The state of gingival health at baseline may be used to determined the frequency of brushing necessary to create or maintain healthy gingivae.

Animals↗