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Biomedical subjects

L Jalkanen

Publications and source records attributed to L Jalkanen.

23 records · Page 2Linked to original sources

Long-term effects of cessation of smoking on body weight, blood pressure and serum cholesterol in the middle-aged population with high blood pressure.

Smoking habits are continuously changing in the population. Cessation of smoking is not only often difficult but may lead to undesired consequences, esp. to weight gain. A random sample of 2283 persons with mild hypertension was followed up for 5 years in Eastern Finland and examined at the community-based cardiovascular program. During that time 30% of those smoking initially stopped smoking. Men gained weight on the average 3.6 kg upon stopping smoking (p less than 0.001) after controlling for age, change in fat and sugar intake and change in physical activity at leisure time). In women cessation of smoking was not related to weight changes. There was no evidence in this follow-up that smoking or cessation of smoking would have any independent impact on blood pressure or serum total cholesterol level.

Adult↗

Factors associated with changes in body weight during a five-year follow-up of a population with high blood pressure.

In 1972 a cardiovascular disease prevention programme was started in North Karelia in Eastern Finland. At the outset of the programme a random sample comprising 10940 persons aged 25 to 59 years was studied. Those subjects whose systolic blood pressure was greater than or equal to 175 and/or diastolic greater than or equal to 100 mmHg or who were undergoing antihypertensive treatment, were re-examined in 1977. Their body weight was measured both in 1972 and 1977. The changes in their physical activity, smoking and eating habits were also interviewed. The men aged 25 to 49 years had increased their body mass index by 0.4 kg/m2 and the men aged 50 to 59 years by 0.2 kg/m2, on average. In women (aged 25 to 49 years) body mass index had increased by 0.5 kg/m2 but decreased in the age group 50 to 59 years by 0.2 kg/m2, on average. In men the change in body weight exerted the strongest partial regression on the change in smoking, age and physical activity (both in leisure time and at work). In women aged 25 to 49 years the reasons for increased body weight were the same as in men. In older women, aged 50 to 59 years the decrease in body weight was associated with age, change in amount of smoking and initiation of antihypertensive drug therapy.

Adult↗

Relationship between hyponeophagia and adrenal cortex function in farmed foxes.

The adrenal cortex function of farmed blue (Alopex lagopus) and silver foxes (Vulpes vulpes) differing in their reaction in the feeding test were assessed. The urine cortisol:creatinine ratio was lower for those animals eating in the feeding test in comparison to those not eating in both species. In addition, eater silver foxes had lower baseline serum cortisol concentration and also lower serum cortisol concentration 2 h after ACTH administration than noneaters. There were no differences in any serum cortisol levels between the eater and noneater blue foxes. The weights of body and adrenals did not differ between confident and fearful animals in either species. The present study demonstrates that animals not eating in the feeding test may have higher fearfulness and be more stressed than animals eating.

Adrenal Cortex↗

[The reproductive function of young male silver foxes Vulpes vulpes after long-term selection for domesticated behavior].

Sperm morphology of spermaries, testosterone plasma level and sexual activity of young silver fox males selected for domestic behavior have been studied. It is established that a number of spermatozoa in semen of males from selected population is lower as compared with the control one, whereas abnormal spermatogenesis level is significantly increased. The testosterone plasma level in males after a female introduction increased to the same extent in both groups. Sexual activity in males from selected population was lower than in the control one during the first mating season. The data obtained suggest a depressing effect of selection for domestic behavior on spermatogenesis and sexual activity in the young silver fox males and point to the hereditary changes of some chains of reproductive functions of males under the selection for domestic behavior.

Animals↗