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L K Jackson

Publications and source records attributed to L K Jackson.

21 records · Page 2Linked to original sources
PubMed1976

14C-Labeled aflatoxin B1 prepared with yeastlike cultures of Aspergillus parasiticus.

A simple method was developed to produce 14C-labeled aflatoxin B1 by using the yeastlike phase of Aspergillus parasiticus NRRL 2999. Yeastlike cultures resulted from absence of manganese in a synthetic medium. Sodium acetate-1-14C had a 0.22% average incorporation; sodium acetate-1,2-14C, 0.70%. The average yield of labeled B1 was 10 mg/500 ml medium with an average specific activity of either 63.3 mCi/mole (C-1 label) or 194.3 mCi/mole (C-1, 2 label).

Acetates↗
PubMed1976

Teratogenicity of patulin and patulin adducts formed with cysteine.

The mean lethal dose of patulin for the chicken embryo injected in the air cell before incubation was determined to be 68.7 mug and that for the 4-day-old embryo was 2.35 mug. Both patulin (1 to 2 mug/egg) and the reaction mixture between patulin and cysteine (15 to 150 mug of patulin equivalents) were teratogenic to the chicken embryo. At least two ninhydrin-negative and four ninhydrin-positive products were formed during the latter reaction. Our explanation of the reaction mechanism remains to be elaborated.

Animals↗