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Biomedical subjects

L K Scott

Publications and source records attributed to L K Scott.

6 recordsLinked to original sources
PubMed1989

Respiration and osmoregulation of the estuarine crab, Rhithropanopeus harrisii (Gould): effects of the herbicide, alachlor.

1. The effects of a sudden decrease in salinity and exposure to sublethal concentrations of the herbicide, alachlor, on osmoregulation and respiration of the crab, Rithropanopeus harrisii, were studied. 2. Crabs were hyperosmotic regulators at salinities below 24 ppt and became hypoosmotic at higher salinities. Upon a salinity decrease from 20 to 1 ppt, crabs adjusted their haemolymph osmolality to a stable hyperosmotic level in 8 hr. Alachlor concentrations to 50 ppm did not affect this adjustment. 3. A salinity decrease from 10 to 0 ppt elevated VO2 and the critical oxygen tension. This response was unaffected by alachlor concentrations as high as 25 ppm.

Acetamides↗
PubMed1978

An evaluation of the effectiveness of audio cassettes for CME.

Medical teachers and practising doctors were surveyed by questionnaire and given pre- and post-tests to determine the efficiency and effectiveness of Practical Reviews in Cancer Management, a cassette tape programme of continuing medical education (CME). Doctors indicated a high degree of satisfaction with this approach; in particular the idea of keeping abreast of the current literature while commuting in their cars was appealing. The programme's effectiveness was measured by pre- and post-tests, and the data were analysed by the non-directional t-test for dependent groups. These tests indicated a significant (P less than 0.001) increase in knowledge from the pre- to post-tests.

Alabama↗
PubMedDate not supplied

Quinolone antibiotics in the treatment of Salmonella infections.

The 4-fluoroquinolones are a new class of antimicrobial agents that possess broad in vitro antibacterial activity, including efficacy against enteric pathogens such as Salmonella, Shigella, Campylobacter, Yersinia, and Vibrio species. These drugs are clinically effective against both drug-sensitive and multiresistant strains of Salmonella typhi and Salmonella paratyphi that cause enteric fever. In salmonella enterocolitis, the quinolones--unlike older antimicrobial agents that may have little impact on the duration of symptomatic illness and can in fact prolong fecal carriage of salmonellae--actually shorten the course of clinical disease and terminate excretion of these organisms in the stool. Similarly, for chronic carriers of both typhoidal and nontyphoidal Salmonella strains, the quinolones are effective in eradicating biliary and fecal reservoirs of infection. Immunosuppressed persons with salmonellosis, such as those with AIDS, may benefit from both short-term treatment and prolonged prophylaxis with a quinolone antibiotic. The optimal agent, dose, and duration of quinolone therapy for all salmonella syndromes remain to be determined by larger controlled trials.

4-Quinolones↗