Biomedical subjects
Publications and source records attributed to L K Smirnova.
Experiments were conducted on albino rats; injury of the ventro-medial portion of the hypothalamus or section of its nervous bonds was accompanied by hyperinsulinemia, which may serve, along with hyperphagia, as a direct cause of adiposity.
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The content of prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol, and progesteron was determined in the blood serum during normal menstrual cycle in 11 healthy women aged from 20 to 35 years. Radioimmunological method indicated the changes in prolactin level during the cycle, as well as in the FSH and LH levels, to be cyclic in character. Prolactin peak revealed in the middle of the cycle coincided with LH and FSH peaks in time. Prolactin and LH level was greater during the lutein than during the folliculin phase; the contrary was true of the FSH level--it was greater in the course of folliculin than during the lutein phase. A postitive correlation was revealed bwtween the prolactin, FSH and LH levels during the cycle, between the FSH and estradiol levels--during the 1st phase and between the LH and progesteron levels--during the 2nd phase of the cycle. However, this correlation between the prolactin and ovarian hormone levels was weak and statistically insignificant.
The blood plasma prolactin concentration was studied by radioimmunoassay in males of different age. The hormone level changed depending on age. A decrease in the reproductive function of the males over 40 years can be due to a fall of the blood plasma prolactin content.
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