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Biomedical subjects

L KILHAM

Publications and source records attributed to L KILHAM.

At least 19 recordsLinked to original sources
PubMed1965

CEREBELLAR DISEASE IN CATS INDUCED BY INOCULATION OF RAT VIRUS.

Rat virus selectively destroys the external germinal layer of the cerebellar cortex when inoculated intracerebrally into newborn cats. The lesions are marked by numerous intranuclear inclusion bodies and a rise of virus titers. These effects suggest that the spontaneous ataxia of cats which is accompanied by cerebellar hypoplasia, may be of viral origin.

Animals↗
PubMed1964

CONGENITAL ANOMALIES INDUCED IN HAMSTER EMBRYOS WITH H-1 VIRUS.

Intravenous injection of H-1 virus into pregnant hamsters early in gestation produces an embryocidal and teratogenic effect. The congenital malformations, the presence of inclusion bodies in the fetuses, and the fact that the maternal animals are not affected by this virus, are points of similarity to the teratogenic effects of rubella virus and cytomegalic-inclusion disease virus in man.

Animals↗
PubMed1964

CEREBELLAR ATAXIA IN HAMSTERS INOCULATED WITH RAT VIRUS.

Chronic ataxia associated with hypoplasia of the cerebellum was induced by intracerebral inoculation of newborn hamsters with various strains of rat virus. The condition usually became recognizable within 3 weeks of inoculation and remained static as the animals matured. Preliminary studies suggest that hypoplasia is induced by the rat virus acting on the outer germinal layer of the cerebellum at a critical time in its ontogenic development.

Animals↗